Certifications 2
SDS No.: 153630 V007.0
LOCTITE LB 8023
Page 15 of 21
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
diboron trioxide
1303-86-2
not carcinogenic
oral: feed
103 w
daily
mouse
male/female
OECD Guideline 451
(Carcinogenicity
Studies)
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Calcium oxide
1305-78-8
NOAEL P > 1.000 mg/kg
oral: gavage
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
diboron trioxide
1303-86-2
NOAEL P 336 mg/kg
NOAEL F1 100 mg/kg
NOAEL F2 100 mg/kg
three-
generation
study
oral: feed
rat
not specified
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Calcium oxide
1305-78-8
NOAEL 1.000 mg/kg
oral: gavage
up to 48 consecutive
days
daily
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
(C16-
C24)Alkylbenzenesulfoni
c acid, Ca
70024-69-0
NOAEL 500 mg/kg
oral: gavage
29 d
daily
rat
OECD Guideline 407
(Repeated Dose 28-Day
Oral Toxicity in Rodents)
Benzenesulfonic acid,
C10-16-alkyl derivs.,
calcium salts
68584-23-6
NOAEL 500 mg/kg
oral: gavage
29 d
daily
rat
OECD Guideline 407
(Repeated Dose 28-Day
Oral Toxicity in Rodents)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
NOAEL 1.000 mg/kg
oral: gavage
28 d
daily
rat
OECD Guideline 407
(Repeated Dose 28-Day
Oral Toxicity in Rodents)
diboron trioxide
1303-86-2
NOAEL 100 mg/kg
oral: feed
2 y
daily
rat
not specified