Certifications 2

SDS No.: 153630 V006.0
LOCTITE LB 8023
Page 12 of 18
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Calcium oxide
1305-78-8
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
EPA OPPTS 870.5265 (The
Salmonella typhimurium
Bacterial Reverse Mutation
Test)
Calcium oxide
1305-78-8
negative
mitotic
recombination in
Sacch. cerevisiae
with and without
OECD Guideline 481 (Genetic
Toxicology: Saccharomyces
cerevisiae, Mitotic
Recombination Assay)
Calcium dihydroxide
1305-62-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
(C16-
C24)Alkylbenzenesulfoni
c acid, Ca
70024-69-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
(C16-
C24)Alkylbenzenesulfoni
c acid, Ca
70024-69-0
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
(C16-
C24)Alkylbenzenesulfoni
c acid, Ca
70024-69-0
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Benzenesulfonic acid,
C10-16-alkyl derivs.,
calcium salts
68584-23-6
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Benzenesulfonic acid,
C10-16-alkyl derivs.,
calcium salts
68584-23-6
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Benzenesulfonic acid,
C10-16-alkyl derivs.,
calcium salts
68584-23-6
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Boron oxide (B2O3)
1303-86-2
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
not specified
Boron oxide (B2O3)
1303-86-2
negative
mammalian cell
gene mutation assay
with and without
not specified
Boron oxide (B2O3)
1303-86-2
negative
sister chromatid
exchange assay in
mammalian cells
with and without
not specified
(C16-
C24)Alkylbenzenesulfoni
c acid, Ca
70024-69-0
negative
intraperitoneal
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Benzenesulfonic acid,
C10-16-alkyl derivs.,
calcium salts
68584-23-6
negative
intraperitoneal
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Boron oxide (B2O3)
1303-86-2
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)