Certifications 2

SDS No.: 242144 V008.1
LOCTITE LB 8008 C5-A known as 8008-C5-A 453g Brush-Top,
Page 10 of 15
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Calcium dihydroxide
1305-62-0
Category 1
(irreversible
effects on the
eye)
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Copper
7440-50-8
not irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Copper
7440-50-8
not sensitising
Guinea pig maximisation
test
guinea pig
EU Method B.6 (Skin Sensitisation)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Calcium dihydroxide
1305-62-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Distillates (petroleum),
hydrotreated light
naphthenic < 3% DMSO
64742-53-6
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Copper
7440-50-8
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Copper
7440-50-8
negative
oral: gavage
mouse
EU Method B.12
(Mutagenicity
Copper
7440-50-8
negative
oral: gavage
rat
equivalent or similar to OECD
Guideline 486 (Unscheduled
DNA Synthesis (UDS) Test
with Mammalian Liver Cells
in vivo)
Carcinogenicity
No data available.
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Copper
7440-50-8
NOAEL P 1500 ppm
NOAEL F1 1000 ppm
NOAEL F2 1000 ppm
two-
generation
study
oral: feed
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
Copper
7440-50-8
NOAEL P 1000 ppm
NOAEL F1 1000 ppm
NOAEL F2 1000 ppm
two-
generation
study
oral: feed
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)