Certifications 2

SDS No.: 153766 V008.1
LOCTITE EA 3463 known as Loctite 3463
Page 8 of 13
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
not irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 472 (Genetic
Toxicology: Escherichia coli,
Reverse Mutation Assay)
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
negative
oral: gavage
mouse
not specified
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
not carcinogenic
dermal
2 y
daily
mouse
male
OECD Guideline 453
(Combined Chronic
Toxicity /
Carcinogenicity
Studies)
reaction product:
bisphenol-A-
(epichlorhydrin); epoxy
resin (number average
molecular weight700)
25068-38-6
not carcinogenic
oral: gavage
2 y
daily
rat
male/female
OECD Guideline 453
(Combined Chronic
Toxicity /
Carcinogenicity
Studies)