Certifications 2

MSDS-No.: 153766
V006.0
LOCTITE EA 3463 known as Loctite 3463
Page 10 of 12
Reproductive toxicity:
Hazardous substances
CAS-No.
Result / Classification
Species
Exposure
time
Species
Method
Epoxy resin (number
average molecular weight
≤ 700)
25068-38-6
NOAEL P = >= 50 mg/kg
NOAEL F1 = >= 750 mg/kg
NOAEL F2 = >= 750 mg/kg
Two
generation
study
oral: gavage
238 d
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Epoxy resin (number
average molecular weight
≤ 700)
25068-38-6
NOAEL=50 mg/kg
oral: gavage
14 wdaily
rat
OECD Guideline 408
(Repeated Dose 90-Day Oral
Toxicity in Rodents)
SECTION 12: Ecological information
General ecological information:
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria for
mixtures for each hazard class or differentiation in Annex I to Regulation (EC) No 1272/2008. Relevant available
health/ecological information for the substances listed under Section 3 is provided in the following.
12.1. Toxicity
Ecotoxicity:
Do not empty into drains / surface water / ground water.
Harmful to aquatic life with long lasting effects.
Hazardous components
CAS-No.
Value
type
Value
Acute
Toxicity
Study
Exposure
time
Species
Method
Epoxy resin (number average
molecular weight ≤ 700)
25068-38-6
LC50
1,75 mg/l
Fish
96 h
Oncorhynchus mykiss
OECD Guideline
203 (Fish, Acute
Toxicity Test)
Epoxy resin (number average
molecular weight ≤ 700)
25068-38-6
EC50
1,7 mg/l
Daphnia
48 h
Daphnia magna
OECD Guideline
202 (Daphnia sp.
Acute
Immobilisation
Test)
Epoxy resin (number average
molecular weight ≤ 700)
25068-38-6
EC50
> 11 mg/l
Algae
72 h
Scenedesmus capricornutum
OECD Guideline
201 (Alga, Growth
Inhibition Test)
NOEC
4,2 mg/l
Algae
72 h
Scenedesmus capricornutum
OECD Guideline
201 (Alga, Growth
Inhibition Test)
Epoxy resin (number average
molecular weight ≤ 700)
25068-38-6
IC50
> 100 mg/l
Bacteria
3 h
activated sludge, industrial
other guideline:
Epoxy resin (number average
molecular weight ≤ 700)
25068-38-6
NOEC
0,3 mg/l
chronic
Daphnia
21 d
Daphnia magna
OECD 211
(Daphnia magna,
Reproduction Test)
12.2. Persistence and degradability
Persistence and Biodegradability:
The product is not biodegradable.
Hazardous components
CAS-No.
Result
Route of
application
Degradability
Method