Certifications 2

SDS No.: 313071 V005.3
LOCTITE 4860
Page 10 of 15
Acute inhalative toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Test atmosphere
Exposure
time
Species
Method
Dibenzoyl peroxide
94-36-0
LC50
> 24,3 mg/l
vapour
4 h
rat
not specified
Skin corrosion/irritation:
Bonds skin in seconds. Considered to be of low toxicity: acute dermal LD50 (rabbit)>2000mg/kg
Due to polymerisation at the skin surface allergic reaction is unlikely to occur
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
slightly
irritating
24 h
rabbit
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Serious eye damage/irritation:
Liquid product will bond eyelids. In a dry atmosphere (RH<50%) vapours may cause irritation and lachrymatory effect
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
irritating
72 h
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
not sensitising
guinea pig
not specified
Hydroquinone
123-31-9
sensitising
Guinea pig maximisation
test
guinea pig
not specified
Dibenzoyl peroxide
94-36-0
sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Ethyl 2-cyanoacrylate
7085-85-0
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethyl 2-cyanoacrylate
7085-85-0
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Hydroquinone
123-31-9
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
EU Method B.13/14
(Mutagenicity)
Carcinogenicity
No data available.
Reproductive toxicity:
No data available.