Certifications 2

SDS No.: 173071 V009.0
LOCTITE SF 7200 400ML EGFD
Page 15 of 22
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Propane
74-98-6
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Propane
74-98-6
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Propan-2-ol
67-63-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Propan-2-ol
67-63-0
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethanol
64-17-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Ethanol
64-17-5
negative
in vitro mammalian
chromosome
aberration test
without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Ethanol
64-17-5
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Butanone
78-93-3
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
2-aminoethanol
141-43-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
2-aminoethanol
141-43-5
negative
in vitro mammalian
chromosome
aberration test
without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
2-aminoethanol
141-43-5
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Propane
74-98-6
negative
Drosophila
melanogaster
not specified
Propane
74-98-6
negative
inhalation: gas
rat
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Propan-2-ol
67-63-0
negative
intraperitoneal
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Ethanol
64-17-5
negative
OECD Guideline 475
(Mammalian Bone Marrow
Chromosome Aberration Test)
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
Drosophila
melanogaster
not specified
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
inhalation: gas
rat
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
2-aminoethanol
141-43-5
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)