Certifications 2

SDS No.: 444476 V003.0
LOCTITE SI 5990 known as Loctite SI 5990 40 ML EDFN
Page 9 of 16
Acute dermal toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Species
Method
octamethylcyclotetrasilox
ane
556-67-2
LD50
> 2.375 mg/kg
rat
equivalent or similar to OECD Guideline 402 (Acute
Dermal Toxicity)
Dodecamethylcyclohexasi
loxane
540-97-6
LD50
> 2.000 mg/kg
rat
OECD Guideline 402 (Acute Dermal Toxicity)
Dimethyltindineodecanoat
e
68928-76-7
LD50
> 2.000 mg/kg
rat
OECD Guideline 402 (Acute Dermal Toxicity)
Acute inhalative toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Test atmosphere
Exposure
time
Species
Method
octamethylcyclotetrasilox
ane
556-67-2
LC50
36 mg/l
dust/mist
4 h
rat
OECD Guideline 403 (Acute
Inhalation Toxicity)
Skin corrosion/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
octamethylcyclotetrasilox
ane
556-67-2
not irritating
rabbit
equivalent or similar to OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)
Dodecamethylcyclohexasi
loxane
540-97-6
not irritating
4 h
rabbit
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Dimethyltindineodecanoat
e
68928-76-7
irritating or
corrosive
15 min
Human,
EpiSkinTM
(SM),
Reconstructed
Human
Epidermis (RHE)
OECD Guideline 439 (In Vitro Skin Irritation:
Reconstructed Human Epidermis (RHE) Test Method)
Dimethyltindineodecanoat
e
68928-76-7
not corrosive
1 h
Human,
EpiDermTM SIT
(EPI-200),
Reconstructed
Human
Epidermis (RHE)
OECD Guideline 431 (In Vitro Skin Corrosion:
Reconstructed Human Epidermis (RHE) Test Method)
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
octamethylcyclotetrasilox
ane
556-67-2
not irritating
rabbit
equivalent or similar to OECD Guideline 405 (Acute Eye
Irritation / Corrosion)
Dodecamethylcyclohexasi
loxane
540-97-6
not irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)