Certifications 2

SDS No.: 153749 V004.1
LOCTITE LB 8009
Page 8 of 12
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Calcium fluoride
7789-75-5
not sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Calcium fluoride
7789-75-5
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Calcium fluoride
7789-75-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Calcium fluoride
7789-75-5
negative
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Distillates (petroleum),
hydrotreated light
naphthenic < 3% DMSO
64742-53-6
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Carcinogenicity
No data available.
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Calcium fluoride
7789-75-5
NOAEL P 250 ppm
NOAEL F1 250 ppm
two-
generation
study
oral:
drinking
water
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Calcium fluoride
7789-75-5
inhalation:
aerosol
28 d
6 hours/day, 5
days/week
rat
OECD Guideline 412
(Repeated Dose
Inhalation Toxicity:
28/14-Day)