Certifications 2

MSDS-No.: 283259
V003.1
LOCTITE LB 8192 known as LOCTITE 8192 400ML En/De/Fr/Nl.
Page 7 of 11
Acute oral toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Propan-2-ol
67-63-0
LD50
5.338 mg/kg
oral
rat
Acute inhalative toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Propan-2-ol
67-63-0
LC50
72,6 mg/l
4 h
rat
Butane, n- (< 0.1 %
butadiene)
106-97-8
LC50
658 mg/l
4 h
rat
Acute dermal toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Propan-2-ol
67-63-0
LD50
12.870 mg/kg
dermal
rabbit
Skin corrosion/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Propan-2-ol
67-63-0
slightly irritating
4 h
rabbit
OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)
Serious eye damage/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Propan-2-ol
67-63-0
moderately irritating
rabbit
OECD Guideline 405 (Acute
Eye Irritation / Corrosion)
Respiratory or skin sensitization:
Hazardous components
CAS-No.
Result
Test type
Species
Method
Propan-2-ol
67-63-0
not sensitising
Buehler
test
guinea pig
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Propan-2-ol
67-63-0
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
Propane
74-98-6
negative with
metabolic
activation
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Propan-2-ol
67-63-0
NOAEL=1500
inhalation
13 weeks6 hours/day,
5 days/week
mouse
Propan-2-ol
67-63-0
LOAEL=5000
inhalation
13 weeks6 hours/day,
5 days/week
mouse