Certifications 2

SDS No.: 283259 V004.0
LOCTITE LB 8192 known as Loctite 8192
Page 11 of 15
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Propan-2-ol
67-63-0
NOAEL P 853 mg/kg
One
generation
study
oral:
drinking
water
rat
equivalent or similar to
OECD Guideline 415 (One-
Generation Reproduction
Toxicity Study)
Propan-2-ol
67-63-0
NOAEL P 500 mg/kg
NOAEL F1 1.000 mg/kg
Two
generation
study
oral: gavage
rat
equivalent or similar to
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
Butane, n- (< 0.1 %
butadiene)
106-97-8
NOAEL P 21,4 mg/l
NOAEL F1 21,4 mg/l
screening
inhalation:
gas
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
Propane
74-98-6
NOAEL P 21,6 mg/l
NOAEL F1 21,6 mg/l
screening
inhalation:
gas
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
Isobutane
75-28-5
NOAEL P 21,4 mg/l
NOAEL F1 21,4 mg/l
screening
inhalation:
gas
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Propan-2-ol
67-63-0
inhalation:
vapour
at least 104 w
6 h/d, 5 d/w
rat
OECD Guideline 451
(Carcinogenicity Studies)
Butane, n- (< 0.1 %
butadiene)
106-97-8
inhalation:
gas
28 d
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
Propane
74-98-6
inhalation:
gas
28 d
6 h/d, 7 d/w
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
Isobutane
75-28-5
inhalation:
gas
28 d
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
Aspiration hazard:
No data available.