Certifications 2

MSDS-No.: 153465
V005.0
Loctite 272 Threadlocker
Page 9 of 14
SECTION 11: Toxicological information
11.1. Information on toxicological effects
General toxicological information:
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria for
mixtures for each hazard class or differentiation in Annex I to Regulation 1272/2008/EC. Relevant available health/ecological
information for the substances listed under Section 3 is provided in the following.
STOT-single exposure:
May cause respiratory irritation.
Oral toxicity:
May cause irritation to the digestive tract.
Skin irritation:
Causes skin irritation.
Eye irritation:
Causes serious eye damage.
Sensitizing:
May cause an allergic skin reaction.
Acute oral toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
N,N-(m-
phenylene)dimaleimide
3006-93-7
LD50
2.025 mg/kg
oral
rat
Hydroxypropyl
methacrylate
27813-02-1
LD50
> 2.000 mg/kg
oral
rat
OECD Guideline 401 (Acute
Oral Toxicity)
Cumene hydroperoxide
80-15-9
LD50
550 mg/kg
oral
rat
Maleic acid
110-16-7
LD50
708 mg/kg
oral
rat
Acute dermal toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Hydroxypropyl
methacrylate
27813-02-1
LD50
> 5.000 mg/kg
dermal
rabbit
Maleic acid
110-16-7
LD50
1.560 mg/kg
dermal
rabbit
Skin corrosion/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Cumene hydroperoxide
80-15-9
corrosive
rabbit
Draize Test
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Cumene hydroperoxide
80-15-9
positive
bacterial reverse
mutation assay (e.g
Ames test)
without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Cumene hydroperoxide
80-15-9
negative
dermal
mouse