Certifications 2

SDS No.: 153465 V009.0
LOCTITE 272
Page 15 of 21
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
Hydroxypropyl
methacrylate
27813-02-1
not carcinogenic
inhalation
2 years (102
weeks)
6 hours/day,
5 days/week
rat
male
OECD Guideline 451
(Carcinogenicity
Studies)
maleic acid
110-16-7
not carcinogenic
oral: feed
2 y
daily
rat
male/female
OECD Guideline 451
(Carcinogenicity
Studies)
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
NOAEL P 250 mg/kg
NOAEL F1 1.000 mg/kg
oral: gavage
rat
OECD Guideline 421
(Reproduction /
Developmental Toxicity
Screening Test)
N,N-(m-
phenylene)dimaleimide
3006-93-7
NOAEL P 240 mg/kg
NOAEL F1 240 mg/kg
screening
oral: gavage
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
Hydroxypropyl
methacrylate
27813-02-1
NOAEL P 400 mg/kg
two-
generation
study
oral: gavage
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
maleic acid
110-16-7
NOAEL F1 150 mg/kg
NOAEL F2 55 mg/kg
Two
generation
study
oral: gavage
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
NOAEL 300 mg/kg
oral: gavage
4 weeks
daily
rat
OECD Guideline 407
(Repeated Dose 28-Day
Oral Toxicity in Rodents)
N,N-(m-
phenylene)dimaleimide
3006-93-7
NOAEL 15 mg/kg
oral: gavage
42-52 d
daily
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
Hydroxypropyl
methacrylate
27813-02-1
NOAEL 300 mg/kg
oral: gavage
rat
OECD Guideline 422
(Combined Repeated
Dose Toxicity Study with
the Reproduction /
Developmental Toxicity
Screening Test)
Cumene hydroperoxide
80-15-9
inhalation:
aerosol
6 h/d
5 d/w
rat
not specified
maleic acid
110-16-7
NOAEL >= 40 mg/kg
oral: feed
90 d
daily
rat
OECD Guideline 408
(Repeated Dose 90-Day
Oral Toxicity in Rodents)