Certifications 2

SDS No.: 153465 V009.0
LOCTITE 272
Page 14 of 21
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
not sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
N,N-(m-
phenylene)dimaleimide
3006-93-7
not sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
Hydroxypropyl
methacrylate
27813-02-1
sensitising
Guinea pig maximisation
test
guinea pig
not specified
maleic acid
110-16-7
sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
maleic acid
110-16-7
sensitising
Mouse local lymphnode
assay (LLNA)
guinea pig
OECD Guideline 406 (Skin Sensitisation)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
in vitro mammalian
cell micronucleus
test
with and without
OECD Guideline 487 (In vitro
Mammalian Cell
Micronucleus Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
positive
in vitro mammalian
cell micronucleus
test
with and without
OECD Guideline 487 (In vitro
Mammalian Cell
Micronucleus Test)
Ethoxylated bisphenol A
dimethacrylate esters
41637-38-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
N,N-(m-
phenylene)dimaleimide
3006-93-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Hydroxypropyl
methacrylate
27813-02-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Hydroxypropyl
methacrylate
27813-02-1
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Cumene hydroperoxide
80-15-9
positive
bacterial reverse
mutation assay (e.g
Ames test)
without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
maleic acid
110-16-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
no data
Ames Test
maleic acid
110-16-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)










