Leica ASP300 Advanced Smart Processor Automated vacuum tissue processor Instruction manual Leica ASP300 V1.3 English - 12/2003 Always keep this manual together with the instrument. Read this instruction manual carefully before working with the instrument.
NOTE The information, numerical data, notes and value judgments contained in this manual represent the current state of scientific knowledge and state-of-the-art technology. We are under no obligation to update the present manual according to the latest technical developments, nor to provide our customers with additional copies, updates etc. of this manual. For erroneous statements, drawings, technical illustrations etc.
Table of contents 1. Important notes ............................................................................................................................. 6 1.1 1.2 2. Safety .............................................................................................................................................. 7 2.1 2.2 2.3 3. Site requirements ..................................................................................................................... 19 Electrical connection....
Table of contents 5.2.6 5.2.7 5.3 5.3.1 5.3.2 5.4 5.5 5.6 5.7 6. Trouble shooting ........................................................................................................................ 56 6.1 6.2 6.3 6.4 7. General ....................................................................................................................................... 56 Power failure ..........................................................................................................................
1. Important notes 1.1 Symbols used in this manual and their meaning Warnings appear in a grey box and are marked by a warning triangle . Notes, i.e. important user information appear in a grey box and are marked by an information symbol . Flammable solvents and reagents are marked with this symbol. 1.2 Designated use The Leica ASP300 is an automated tissue processor for the following laboratory applications: • fixation • dehydration • paraffin wax infiltration of histological tissue specimens.
2. Safety Make sure to comply with the safety instructions and warnings in this chapter. Make sure to read these instructions, even if you are already familiar with the operation and use of other Leica products. 2.1 Safety instructions This instruction manual includes important information related to the operating safety and maintenance of the instrument and it is an important part of the product.
2. Safety 2.2 Warnings The safety devices installed in this instrument by the manufacturer only constitute the basis for accident prevention. Primarily responsible for accident-free operation is above all the institution which owns the instrument and, in addition, the designated personnel who operates, services or repairs the instrument. To ensure trouble-free operation of the instrument, make sure to comply with the following instructions and warnings.
2. Safety Warnings - cleaning and maintenance Prior to each maintenance switch the instrument off and disconnect mains power. Do not clean the instrument with solvents containing acetone or xylene. No liquid may be spilled into the internal components of the instrument. Empty the condensate bottle at regular intervals. Warnings - working with the instrument The Leica ASP300 may only be operated by trained laboratory personnel and as per the present instruction manual.
2. Safety 2.3 Integrated safety devices The instrument is equipped with the following protection features: • overpressure protection, • protection against excessive vacuum, • overcurrent protection, • overheating protection. Overpressure protection The design of the pressure system ensures that no dangerous levels of pressure can build up. Protection against excessive vacuum The vacuum system is not capable of generating a dangerous vacuum condition.
3. Instrument components and specifications 3.1 Specific instrument options • Reagent Management System (RMS). • The specimen cassette baskets may be used with or without cassette dividers and spring separators designed to separate cassettes and improve fluid penetration. • In-process fluid recirculation (‘tidal agitation’) for continuous and efficient mixing of fluids. • Remote fill/drain system for reagents. • Remote fill/drain system for paraffin. • Automatic optical fluid level sensor.
3. Instrument components and specifications 3.2 Overview - instrument components 3 4 23 6 1 22 7 5 10 9 21 20 12 11 8 19 13 17 18 2 15 14 16 Fig. 1 12 Instruction manual V 1.
3. Instrument components and specifications Overview - Instrument components Instrument components and accessories 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 The processor module comprises three paraffin wax baths and the processing retort. Three baskets (21) contain the cassettes. Each basket can hold up to 300 cassettes. All processing occurs in the stainless steel retort under the pressure, vacuum and temperature conditions selected.
3. Instrument components and specifications 3.3 Standard delivery - packing list Leica ASP300 basic standard delivery: 1 Leica ASP300 - Basic instrument 1 Accessory kit consisting of: - 1 Basket hook 0476 34713 - 3 Specimen baskets, assy., including lid, dividers, springs and handle (accessories for maximum and optimum usage of basket space) - 1 Reagent bottle, plastic - 2 Activated carbon filters, assy. - 1 Remote fill/drain hose, assy.
3. Instrument components and specifications 3.
3. Instrument components and specifications Retort Capacity: Reagent volume (in liters): Temperature (paraffin): Temperature (processing reagents): Temperature (cleaning reagents): Temperature accuracy: Filling time: Drain time : Impregnation vacuum: Impregnation pressure: Fill vacuum: Drain pressure: max. 300 cassettes 4.3 40 to 65 °C ambient or 35 to 55 oC 50 to 65 °C +1K approx. 90 sec approx.
3. Instrument components and specifications 3.4 Technical Data (continued) Hardware and Software: • Large color liquid crystal display (LCD) and touchscreen. • User-friendly, intelligent software. • 3,5“ floppy drive and printer port. • Alarm system with two remote alarm sockets. • Password-protected instrument supervisor mode. • Multiple specimen protection system. Capacities: • 15 programs of up to 10 reagent and 3 paraffin wax steps each. • Time per program step: 0 to 99 hours , 59 minutes.
3. Instrument components and specifications 3.5 Compatible reagents Fixatives 1. Formalin, buffered or unbuffered 2. Formalin saline Dehydration 1. Ethanol 2. Isopropanol 3. Methanol 4. Butanol 5. Industrial Methylated Spirits Clearing 1. Xylen (recommended) * Prior to using these reagents, contact 2. Toluol * your Leica representative or Leica di3. Chloroform * rectly for information on necessary protective measures. Using these reagents Paraffin wax will require an increased number of main1.
4. Setting up the instrument 4.1 Site requirements • • • • • The instrument needs approx. 650 x 700 mm floor space. Practically vibration-free floor. Room temperature constantly between +15 °C and +35 °C. Relative humidity maximum 80%, non-condensing. Avoid vibrations, direct sunlight and heavy variation in temperature. The chemicals to be used in the Leica ASP300 are both flammable and noxious. Therefore, the instrument must be set up in a well ventilated area, free from any ignition sources.
4. Setting up the instrument Connecting the instrument to mains The instrument MUST be connected to an earthed mains power outlet socket. It is recommended that the ASP300 be plugged into a wall socket that has Ground Fault Circuit Interruption (GFCI) protection - as an additional electrical safeguard. Make sure to use the appropriate mains cable for the local voltage supply (wall outlet). • Connect mains cable (6) to mains power supply socket (1) (see Fig. 3).
4. Setting up the instrument 4.3 Installing the accessories 6 7 Fig. 4 • Unpack the activated carbon filter and insert it into the instrument (see Fig. 4). Make sure to insert the filter with the correct side facing upwards. See label (6) at the front of the filter - the arrow must point upwards. • Unpack the magnetic stirrer and insert into the retort. • Install the console flap (covers floppy drive and ports). l Prior to filling the bottles with reagent for the first time, check the connections.
4. Setting up the instrument 4.4 Setting up the data connections 9 Printer (optional) • Lift off the instrument console flap (12). • Connect the printer to the printer port (7) via a standard Centronics cable (refer Fig. 6). 8 7 Other connections • For additional data transfer and storage the instrument console is equipped with a standard 1.44 MB floppy drive (10) for 3.5“ diskettes and with an RS 232 serial port (11) .
4. Setting up the instrument 4.5 Alarm functions The Leica ASP300 is equipped with two different alarm functions: Instrument alarm This alarm is generated from within the Leica ASP300. The instrument alarm is generated in all alarm situations. Remote alarm This alarm device is installed outside of the Leica ASP300. All alarms (all types of alarm) are forwarded to the remote dialer connected to the instrument, regardless of whether the local instrument alarm (type 1) is connected or disconnected.
4. Setting up the instrument 4.6 Switching the instrument on Once the instrument has been switched on, the mains switch (ON/OFF) (5) should always remain in position ON. • After switching it on the instrument will take a few minutes to initialize (see opposite Fig. 7). • After initialization, the FAVORITES screen will be displayed (Fig. 8). Fig. 7 Screen saver • A screen saver will operate turning the screen off when no key has been pressed for a (user-) programmable time.
4. 2 6 3 7 4 8 Setting up the instrument System diagnostics menu If, during initialization, ‘Touch here ...’ is touched (refer Fig. 7) and subsequently the supervisor password is entered, the SYSTEM DIAGNOSTICS menu (Fig. 9) opens up, giving access to standard instrument settings. Attention! Serious instrument malfunctions may occur if any settings are modified wrongly. 1 5 Fig. 9 The following functions can be selected: 1 - Access for service engineers only. 2 - Access INSTALLATION menu.
4. Setting up the instrument 4.7 Touch screen functions 4.7.1 User interface - overview The Leica ASP300 is programmed and operated via a colored LCD touch screen. An on-line help feature provides detailed information on all instrument functions. HELP can be accessed from any screen by pressing the HELP button. Button symbols To activate any functions on the Leica ASP300 touchscreen, press the corresponding button symbols.
4. Setting up the instrument 4.7.2. Access control The Leica ASP300 may be configured to allow two levels of user access. ‘Operator’ symbol Operator access level: • Operators may run programs and view results. On this level, the OPERATOR symbol is displayed in the upper right corner of the touch screen. ‘Supervisor’ symbol → Supervisor access level: • Supervisors may perform all Operator functions, and additionally create programs and perform the instrument sit-up functions.
4. Setting up the instrument 4.8 Check list for first operation (at supervisor access level) → Screen 28 Press button Parameter settings → → Enter instrument name and select language. Activate printer (optional). → → Enter carbon filter age warning and pump warning threshold. → → Set all parameters as required, especially wax bath set temperature. Check whether date and time are correct. → → → Add the desired reagents and edit the ‘REPLACE REAGENTS’ warning thresholds.
5. Operation 5.1 Reagent handling 5.1.1 Fill/drain reagents (other than wax) ↓ ↓ 1. Manually changing the reagents • Remove the appropriate reagent bottle from the Leica ASP300 reagent cabinet, remove the bottle screw cap. • Drain/refill the reagent by pouring to/from a bulk container. • On the REAGENT STATUS screen, verify correct allocation and set the reagent bottle as full. 2.
5. Operation Fill / drain reagents → In FAVORITES, press MENU. In MENU FUNCTIONS, press SMART SCREEN. The SMART SCREEN (Fig. 12) pops up. Fig. 12 Select station Press key symbol Remote drain • On the screen, select reagent bottle no. 3 and the bulk container (Remote). The press STATION DRAIN. • Check for leaks. Remote fill • On the screen, select reagent bottle no. 3 and the bulk container (Remote). The press STATION REFILL. • The remote fill procedure takes less than 3 minutes. • Check for leaks.
5. Operation 5.1.2 Changing the wax 1 2 Fig. 13 Draining the wax • Connect the paraffin drain hose (2) as shown in Fig. 13 and insert the loose end of the hose into a remote collecting container. From the FAVORITES screen, press SMART SCREEN (see previous chapter). → + • Make sure the hose end is securely kept in the remote container until both the drain has been completed and the hose has been purged with pressurized air. → • Select the wax bath to be drained and the remote container (‘Remote’).
5. Operation Filling with wax pellets → • Remove the splash protector. • Fill the wax bath (Fig. 15) with wax pellets up to the top. • Press BACK and REAGENT STATUS to access the reagent status table (Fig. 14). Highlight the wax bath you just filled and press SET AS FULL. • After about 90 minutes, add another 0.5 kg of wax pellets. • The pellets will take a total of approx. 10 hours to melt. → Important! During the melting process, the paraffin level MAY NOT drop below the MIN level (2, Fig. 15). Fig.
5. Operation Adding molten paraffin • Molten wax may have a maximum temperature of 70 °C. • If filling with molten wax, do not fill above the MAX level (see Fig. 15). • After a wax bath has been filled, it must be marked as ‘full’ in the REAGENT STATUS screen. Software control • If the wax baths are filled with molten wax, it is possible to override the Leica ASP300 melting time calculation. → For that purpose, in supervisor mode, access the SERVICE FUNCTIONS screen (Fig. 16).
5. Operation 5.2 Setting up the instrument parameters → From the start screen, press MENU to go to the MENU FUNCTIONS screen, then press MORE. In the MORE MENU FUNCTIONS screen, press SYSTEM SETUP. 5.2.1 System setup SYSTEM SETUP screen (Fig. 17). Fig. 17 The DISPLAY/BUZZER field is practically self-explanatory: • The number next to DISPLAY OFF indicates the remaining time (in min) until the screen saver (after the last user action) is activated. • LCD CONTRAST can be set from 0 to 14.
5. Operation Program Options Selection of the options on how programs are carried out. • STATION ALLOCATION: By age or Sequential By age RMS is activated, reagents will automatically be used in order of increasing cleanliness. Sequential - reagents will be used in sequential order of stations. • WAX BATH ORDER: Auto or 1.; 2. ; 3. Wax bath order can be activated only when STATION ALLOCATION is set to Sequential.
5. Operation Security To determine the level of access to the instrument. • SUPERVISOR PASSWORD: Enabled or Disabled Enabled A password is required for access to the supervisor level. Disabled - • LOCK MODE: Enabled Disabled- All instrument and software functions are fully accessible to all staff. Enabled or disabled. No screen functions can be accessed. To unlock, a password has to be entered. Screen can be accessed at any time until the screen saver turns off the screen.
5. Operation 5.2.2 Editing the reagent list Adding new reagents 1. Enter the reagent name and allocate the new reagent to the reagent group it belongs to. 2. Define the stations (bottles) that will be filled with the new reagent. 3. Fill the stations (bottles) according to the reagent list. → Enter reagent names Enter reagent names via the REAGENTS screen. You must be logged on at supervisor access level to proceed.
5. Operation Allocation of reagents to the correct reagent group is the basis for compatibility monitoring. Allocation to the wrong reagent group can lead to reagent cross contamination. Changeable parameters Entering / modifying reagent thresholds • Highlight the reagent to be modified. • Press the headline key symbol of the parameter to be changed. • Enter a new threshold or - if no warning is desired - press CLEAR to remove the threshold altogether. • Press OK to confirm.
5. ↓ Operation Deleting reagents • Highlight the reagent to be deleted in the SET UP REAGENTS AND WARNING THRESHOLDS screen. • Press DELETE. • Press OK in the screen prompt. Please remember that a reagent which is already used in a program cannot be deleted. Adding new reagents to stations Go to SMART FUNCTIONS to remote-fill the reagent bottle. ↓ ↓ If a bottle is filled manually, it must be defined as full afterwards. For that purpose: • Press MENU to access the MENU FUNCTIONS screen.
5. Operation 5.2.3 Viewing the program list → This list (Fig. 20) displays all programs currently existing in the ASP300. You can create: • up to 15 processing programs, • 3 retort cleaning programs, • 1 wax cleaning program. At supervisor access level: • the processing program names can be edited, • new processing programs can be created and existing ones can be deleted. Fig. 20 Important! New processing programs are created by copying existing ones.
5. Operation 5.2.4 Adding and/or modifying programs Creating a new program • You must be logged on at supervisor level. • In the VIEW/EDIT PROGRAMS screen (Fig. 20) highlight a program as similar as possible to the program you wish to create. • Press COPY to copy the selected program. The new program will have the same name as the program copied, however, the figure “(2)“ will be added. • Highlight the line containing the new program. • Press PROGRAM NAME. • Enter the new program name.
5. Operation Editing program steps • To edit a step, highlight the corresponding line and press the respective headline. • In the entry windows that pop up enter / select the program step settings. ↓ ↓ ↓ ↓ ↓ Fig. 21 42 Instruction manual V 1.
5. Operation Editing program steps (continued) Setting a delay step A so-called ‘delay step’ ensures that a program is finished at a specified time. • Highlight the program step you wish to define as a delay step. • Press DELAY. The delay symbol is moved to the selected step, thus defining the step as delay step. Copying steps • Highlight the step to be copied. • Press COPY.
5. Operation 5.2.5 Favorites (maximum of 5 programs) Favorites can be programmed to end either: • “as soon as possible“ (ASAP) or • at a predetermined finish time. ↓ Fig. 22 ↓ Adding and/or modifying Favorites • Highlight the program line to be altered. • Press PROGRAMS. • Select the desired program and press OK to confirm. Setting a finish time • Press FINISH TIME. • Enter the finish time (24-hour clock). Select ASAP, if the program finish time is not to be delayed. • Press OK to confirm.
5. Operation Assigning a finish day ↓ • Press DAY. • Select the desired week day in the list and press OK to confirm. Assigning an icon to a “Favorite“ • Press SYMBOL in the table header. • Select the desired icon and press OK to confirm. The first icon on the list is empty - select this option, if you do not want to assign an icon to a specific program. ↓ Deleting a ‘Favorite’ • Highlight the Favorite to be deleted. • Press DELETE.
5. Operation 5.2.6 Editing the stations → → Fig. 23 shows all stations / allocated reagents currently defined in the instrument. ↓ Fig. 23 Adding / changing reagents Highlight the desired station. • Press REAGENT NAME. • The SELECT REAGENT entry window pops up. Only those reagents that are compatible with the respective station will be available for selection. • Highlight the desired reagent and press OK to confirm.
5. Operation 5.2.7 Reagent groups → → In this screen (Fig. 24) you find the colors used for each reagent group in the graphic program display. ↓ Fig. 24 Selecting a new color for a reagent group • Highlight the line containing the reagent color you wish to change. • Press COLOR in the table header: the entry window SELECT COLOR pops up. • Select the desired color and press OK to confirm. • If you want to close the entry field without changing the color, press CANCEL.
5. Operation 5.3 Programs Programs can be started from two different screens: ALL PROGRAMS FAVORITES (max. 5 programs) Fig. 25 Fig. 26 A ”Favorite” is a processing program that is frequently used. All settings are already programmed. Only the number of blocks has to be entered (if this function is enabled). In the Favorites screen, press ALL PROGRAMS. Starting a “Favorite“ To start a Favorite, press the corresponding symbol on the Favorites screen - the program will be started immediately.
5. Operation 5.3.1 Editing a selected program Redefine the program finish time: • Press FINISH TIME. In the entry window, set a new finish time. ↓ Fig. 27 To modify a program prior to starting it, press EDIT to access the Edit Program screen. Fig. 28 ↓ • Enter the day when you want the program finished. • Enter the finish time (24-hour clock format). • Press OK to confirm. Fig.
5. Operation Access the RUN OPTIONS function to display the options selected for the current program. • LEVEL CHECK enabled: The lower level sensor in the retort is activated. ↓ • RECIRCULATION enabled: During each processing step, the reagent is pumped periodically from the bottle to the retort and back for continuous and efficient mixing of fluid. The first pump step is carried out after 16 minutes, all subsequent pump steps in 12-minute intervals.
5. Operation 5.3.2 Starting a program ↓ Fig. 31 • Press START to start the program. Press OK to confirm the query that follows. Enter the number of blocks, if the NUMBER OF BLOCKS option has been enabled. • The FINISH TIME button shows the time when the current program will be finished. → • Before a program in progress can be modified, the PAUSE symbol must be pressed. To modify or delete program steps, press EDIT and, in the entry window, carry out any changes you wish to make.
5. Operation 5.4 Reagent status → In the reagent status screen (Fig. 32) you can display and update the actual reagent status of each station and you can set the stations as full or empty. • Warning thresholds that trigger warning messages appear on a red background. • To change a reagent status, highlight the corresponding line and press the corresponding key symbol . Fig.
5. Operation 5.5 System Monitor → → The SYSTEM MONITOR screen supplies important information on the Leica ASP300 system status. PUMP AGE: Indication of hours of service of the pressure/ vacuum pump. After approx. 1,000 hours of use, have Leica Technical Service carry out a preventive maintenance of the pump. CARBON FILTER AGE: Indication of hours of service of the activated carbon filter. The carbon filter must be exchanged after approx. 4 months of use. Fig. 33 After replacing the filter press RESET.
5. Operation 5.6 On-line help The Leica ASP300 features an extensive on-line Help system. For information on basic problems refer to the Help Index (to access press INDEX on the Help screen). Use the UP/ DOWN arrows to scroll. Press PREVIOUS TOPIC (1) to return to the index. Press BACK (2) to go back to the screen from where you accessed Help. CUSTOM HELP (3) is only displayed, if userspecific help files have been installed. 2 1 3 Fig.
5. Operation 5.7 Configuring a printer (optional) → → To select and configure a printer, proceed as follows: • With a Centronics standard cable, connect the printer to the printer port (refer chapter 4.4, Fig. 6). ↓ ↓ Printing run logs Printing is possible when the PRINT symbol is displayed. For the PRINT symbol to be displayed, a printer must have been configured for the instrument.
6. Trouble shooting 6.1 General The Leica ASP300 is equipped with a trouble shooting system. If an error is detected, detailed error messages and corresponding user instructions on what to do are displayed on the touch screen. For all correctable error conditions the instrument will take corrective actions to protect the specimens. → • Details of all events are recorded in “Run Log”. Run log can be viewed by pressing MENU and then RUN LOG. 6.
6. Trouble shooting 6.3 Trouble shooting → • Check for error messages indicating the nature of the problem. • Press the Help button on the message for any information relating to the cause. • Check the Run Log for any information on the nature of the failure. Use the SMART SCREEN functions to individually test operations such as fill, drain, pressurizing and evacuation operations.
6. Trouble shooting 6.4 Typical fill or drain problems Fill and drain problems may be due to several causes: 1. There is insufficient reagent • Verify that both the reagent bottles and the wax stations have sufficient reagent. 2. Insufficient pressure or vacuum The Leica ASP300 is unable to create sufficient vacuum (for a fill) or pressure (for a drain) in the retort. • Verify that the reagent bottle in question is correctly inserted in the reagent cabinet.
7. Cleaning and maintenance 7.1 Clean programs → → You find the clean programs at the end of the programs list (Fig. 35). To display a clean program, highlight the respective line and press EDIT. The ASP300 offers three retort clean programs and one paraffin clean program. Clean programs cannot be copied or deleted. 7.1.1 Retort clean programs A clean program comprises a minimum of three and a maximum of four steps: 1. Cleaning Solvent 1 step from station 11 2.
7. Cleaning and maintenance Editing steps • To edit a program step highlight the corresponding line and press the respective table header. • To disable a step, set the number of cycles to “0“. Only cleaning water steps can be disabled. The following characteristics of each step can be edited: • Reagent name - only those reagents that are compatible with the reagent station being edited will be displayed. • Number of cycles - the duration displayed is calculated based on the number of cycles.
7. 7.1.2 Wax clean programs Cleaning and maintenance The Leica ASP300 contains a wax clean feature that removes solvents (xylene) from used wax. Follow the instructions on the left (Fig. 36) to run a wax clean program. ↓ ↓ Fig. 36 → The duration of the wax clean program is user-programmable. Follow the instructions in Fig. 37. → Fig.
7. Cleaning and maintenance 7.1.3 Smart clean → The Smart Clean prepares the ASP300 for transport. Prior to starting a Smart Clean, a complete retort clean program must be run. To start a Smart Clean, press SMART CLEAN on the MORE MENU FUNCTIONS screen and press OK to confirm. The Smart Clean takes approx. 15 minutes and consists of 3 phases: Phase 1: Make sure all reagent containers are inserted correctly. All internal tubing is cleaned with pressurized air.
7. Cleaning and maintenance 7.2 General cleaning steps Paraffin wax baths Warning! Be careful as the walls of the wax baths are very hot and may cause burns! • Wipe the wax baths and lids clean. The lid can be removed for cleaning purposes. • If they are dirty, remove the wax strainers from the wax baths. Clean, dry and reinsert them. • Ensure that the air vent hole at the top rear right hand corner is unobstructed. Instrument exterior Clean the instrument exterior as necessary.
7. Cleaning and maintenance Draining the condensate bottle • Remove and empty the condensate bottle and reinsert (Fig. 39). Fig.39 Exchanging the activated carbon filter • Exchange the filter as shown in Fig. 40. • Replace the filter at least every four months – make sure to insert correctly – (see arrow on label)! • Perform a Smart Clean prior to changing the filter. Fig. 40 Filter label 64 Instruction Manual V 1.
7. Cleaning and maintenance 7.3.1 Daily cleaning and maintenance Cleaning the retort lid • Remove wax from the inside of the retort lid with the plastic scraper provided. Make sure to remove all wax from around the retort lid seal. • For convenience, the lid may be removed during cleaning by lifting it vertically and sliding it towards the console. Cleaning the retort • The retort may be wiped clean using a cloth moistened with solvent (xylene or alcohol) or mild detergent.
7. Cleaning and maintenance This procedure is particularly important with bottles containing chloroform. Chloroform tends to swell the bottle seals, making them difficult to remove. This problem can be prevented by regular lubrication. Checking the retort and wax bath lid seals • Regularly check the retort and wax bath lid seals for damage. If a seal is damaged, it must replaced without delay. 7.3.
7. Cleaning and maintenance 7.4 Preventative maintenance schedule Maintenance activity daily weekly √ Lubricate reagent bottle O-rings and check for damage. Wipe dry retort and lid after completing retort clean cycle. √ Clean exterior of instrument with soft cloth and minimal amount of xylene. √ Check retort strainer for any tissue or wax debris. √ Remove residual paraffin from inner surface of wax bath lid. √ Inspect and, if necessary, clean retort lid seal.
7. Cleaning and maintenance Maintenance activity daily weekly Inspect and, if necessary, clean wax bath strainers . √ Inspect wax bath air vent and, if necessary, clear. √ Inspect and empty condensate bottle. Clear inlet holes. √ monthly √ Examine activated carbon filter. √ Replace carbon filter. Remove fluid level sensor (float), inspect and clean . √ Inspect electrical connectors at the rear panel of the instrument. √ Inspect and, if necessary, clean inside reagent bottles.
8. Warranty and service Warranty Leica Microsystems Nussloch GmbH guarantees that the contractual product delivered has been subjected to a comprehensive quality control procedure based on the Leica in-house testing standards, and that the product is faultless and complies with all technical specifications and/or agreed characteristics warranted. The scope of the warranty is based on the content of the concluded agreement.
Notice 70 Instruction manual V 1.
