Owner's Manual

How to Perform a Study
NXT Go Owner’s Manual, LBL-00145, MAN2030 40
Urethral Pressure Profile
To start a Urethral Pressure profile (UPP) follow instructions provided in the Customizing
Workflows section on page 56 on adding a UPP phase to a study or select a study template
that contains a UPP phase. Ensure to complete patient and consumables setup as
instructed in the Setting Up Consumables and Preparing the Patient section on page 24.
3.5.2.1 Manual Urethral Pressure Profile
To complete a Manual Urethral Pressure Profile, follow the instructions below:
In the UPP phase, confirm the positioning of urethral pressure sensor (Pura) just
proximal to the bladder neck. To position the sensor, manually withdraw the
catheter at a moderate rate. When Pura begins to rise, stop withdrawing and
return the catheter slightly back into the bladder.
Select the Rest Profile toggle button to start the rest profile.
Begin manually withdrawing the vesical catheter very slowly, pulling at
approximately 1mm/second by using the measurement marking on the catheter.
Vesical pressure should remain stable while urethral pressure and closure pressure
(Pclo) rises and falls indicating that the sensor is travelling through the urethra.
When Pclo returns to zero, stop pulling and reselect the Rest Profile toggle
button to end the profile.
Reinsert the catheter and position just proximal to the bladder neck to complete a
Stress Profile using the Stress Profile toggle button. Once the required number
of profiles is complete, finish the selected study.
3.5.2.2 Mechanical Urethral Pressure Profile
For a Mechanical Urethral Pressure Profile, ensure that the UPP puller NXT is connected in
the Device Manager window. Select the Puller option and set the Puller Speed under
Profile Settings in the Workflow Configuration window before starting the test. To
complete a Mechanical Urethral Pressure Profile, follow the instructions below:
In the UPP phase, confirm positioning of the urethral pressure sensor (Pura) just
proximal to the bladder neck. To position the sensor, manually withdraw the
catheter at a moderate rate. When Pura begins to rise, stop withdrawing and
return the catheter slightly back into the bladder.
Ensure that the UPP Puller is in the start position. If the Rest Profile and Stress
Profile buttons are greyed out in the Synergy Control Panel, click the Puller
Return button to return the UPP Puller to the start position.
Feed the catheter through the Catheter Guide and use the Catheter Clamp to
secure the catheter to the UPP Puller NXT.
Select the Rest Profile (On) toggle button to start the rest profile. The UPP
Puller will begin pulling at the speed selected in the Workflow Configuration.
NOTE: UPP Puller NXT speed can only be adjusted in the Workflow Configuration
window prior to starting the test.
Select the Rest Profile (Off) toggle button to mark the end of the profile. Click
the Puller Return button to return the UPP Puller NXT to the start position.
Manually reinsert the catheter and position just proximal to the bladder neck to
complete a Stress Profile.
Status DRAFT Effective