User’s Manual Protector® Filtered Glove Boxes Base Catalog Model No.
Copyright © 2011 Labconco Corporation. All rights reserved. The information contained in this manual and the accompanying products are copyrighted and all rights reserved by Labconco Corporation. Labconco Corporation reserves the right to make periodic design changes without obligation to notify any person or entity of such change. Warranty Labconco provides a warranty on all parts and factory workmanship.
TABLE OF CONTENTS CHAPTER 1: INTRODUCTION 1 CHAPTER 2: PREREQUISITES Support, Vibration & Preventive Requirements Location Requirements Exhaust and Blower Requirements Particle Testing ISO Class 3 Definition Airflow and Pressure Charts Electrical Requirements Space Requirements 4 5 5 5 6 7 8 12 12 CHAPTER 3: GETTING STARTED Unpacking the Glove Box Installing the Glove Box on a Supporting Structure & Work Surface Connecting to the Exhaust System (If Applicable) Outside Exhaust Connection Diagram Positive
Appropriate HEPA or ULPA Filter Applications, Suitability & Guidelines Definition of Terms Appropriate Chemicals for Carbon Filters Prohibited Acid Use 34 34 35 36 CHAPTER 6: MAINTAINING YOUR GLOVE BOX Routine Maintenance Schedule Decontamination Determining When to Replace Filters How to Install New Filters HEPA or ULPA Filter Leak Test Initial Certification Re-Certification Fluorescent Light Replacement Motorized Impeller Replacement Speed Control Replacement Airflow/Pressure Monitor Circuit Board Repla
Chapter 1: Introduction Congratulations on your purchase of a Labconco Protector® Filtered Glove Box. The stainless steel-lined glove box uses ULPA filters and the fiberglass glove box uses HEPA filters. Your glove box provides personnel protection through superior containment. These glove boxes effectively contain toxic or noxious particulates when properly installed and operated.
Chapter 1: Introduction Protector Stainless Steel ULPA-Filtered Glove Box shown on Adjustable Height Base Stand.
Chapter 1: Introduction Protector Double Width Stainless Steel ULPA-Filtered Glove Box shown on Doublewide Base Stand.
Chapter 2: Prerequisites Before you install the glove box, you need to prepare your site for installation. You must be certain that the area is level and of solid construction. In addition, a dedicated source of electrical power should be located near the installation site to power the glove box. The glove box should be strategically placed in the lab to provide efficient workflow and prevent operator interference from normal traffic patterns.
Chapter 2: Prerequisites Support, Vibration and Preventive Requirements In the preparation of a glove box site, please consider the following: • A bench or stand that is rigidly mounted to the floor or fixed to the wall, but not both, may be appropriate. 35" to 40" (889mm-1016mm) is typical for standing height. (Labconco stands offered in Chapter 7 vary from 33" to 40".) • The corners of a building typically have less vibration than the center, which promotes analytical balance stability.
Chapter 2: Prerequisites Labconco does not recommend hard duct connections with remote blowers due to the air volume balance requirements with such systems. Hard duct connections should only be used when the glove box impeller is disconnected and only a single roof-mounted blower is used. Note that reliance on an external exhaust blower does not provide airflow control at the glove box.
Chapter 2: Prerequisites Protector HEPA-Filtered Glove Box Particle Testing under Positive Pressure 500 NOTE: Ambient Air Baseline Particle Count at 1 Minute 32151 Particles measuring 0.3 Micron detected within 1 Minute. 1074 Particles measuring 0.5 Micron detected within 1 Minute. Number of Particles (Per Cubic Meter Per Minute) 450 400 350 314 300 Airflow Testing Performed at 42 CFM with Glove Box Under Positive Pressure. 269 250 200 150 115 100 > 0.3 Micron 83 98 > 0.
Chapter 2: Prerequisites Additionally, the motorized impeller can also be used in a full recirculation mode providing the operator with some control of the atmosphere chemistry within the glove box. See Chapter 7 for the Recirculation Conversion Kit. The airflow charts below represents typical operational data including air changes per minute, exhaust volume, noise levels, main chamber static pressures, and total system static pressures measured at the blower intake (suction side).
Chapter 2: Prerequisites PROTECTOR HEPA-FILTERED GLOVE BOX (230V) PROTECTOR STAINLESS STEEL HEPA-FILTERED GLOVE BOX (230V) Static Pressure Test Results 2.5 Static Pressure Inside Glove Box Total Static Pressure at Blower Intake (Suction Side) (Inches of Water Column) Negative Static Pressure 2 1.62 1.45 1.5 1.09 1.03 0.93 1 0.81 0.68 0.54 0.49 0.44 0.5 0.32 0.
Chapter 2: Prerequisites PROTECTOR ULPA-FILTERED GLOVE BOX (115V) Static Pressure Test Results 2.41 2.5 Static Pressure Inside Glove Box Total Static Pressure at Blower Intake (Suction Side) (Inches of Water Column) Negative Static Pressure 2 1.91 1.60 1.5 1.36 1.13 1.08 0.90 1 0.75 0.62 0.44 0.5 0.40 0.
Chapter 2: Prerequisites PROTECTOR ULPA-FILTERED GLOVE BOX (230V) PROTECTOR STAINLESS STEEL ULPA-FILTERED GLOVE BOX (230V) Static Pressure Test Results 2.5 Static Pressure Inside Glove Box Total Static Pressure at Blower Intake (Suction Side) (Inches of Water Column) Negative Static Pressure 2 1.67 1.41 1.5 1.23 1.00 0.89 1 0.83 0.72 0.52 0.5 0.51 0.
Chapter 2: Prerequisites For thimble-ducted glove boxes, the proper remote blower selection can be determined from these exhaust requirements as the remote blower only needs to be sized for the static pressure loss of the ductwork system. The thimble ducted exhaust blower should be sized for 25% additional airflow. When exhausting a glove box to the outside, it should be connected to a dedicated remote blower. Labconco offers accessory remote blowers listed in Chapter 7.
Chapter 3: Getting Started Once the site for your Protector Glove Box is properly prepared, you are ready to unpack, inspect, install, and validate your system. Read this chapter to learn how to: • Unpack and move the glove box. • Set up the glove box with the proper supporting structure and work surface. • Connect to an exhaust system if applicable. • Install the gloves. • Connect the electrical supply. • Set the exhaust volume with the speed control adjustment.
Chapter 3: Getting Started Unpacking the Glove Box We recommend that you do not remove the glove box from its shipping container until it is ready to be placed into its final location. Move the unit by placing a flat, low dolly under the shipping skid, or by using a floor jack. Carefully remove the shrink-wrap and crating on the glove box and inspect it for damage that may have occurred in transit.
Chapter 3: Getting Started Connecting to the Exhaust System (If Applicable) ! WARNING: The weight of any exhaust ductwork system must be supported independently of the glove box superstructure or damage may occur. The exhaust system should be installed by a qualified HVAC contractor. The Protector Filtered Glove Box has been manufactured to exhaust into the laboratory in its standard configuration.
Chapter 3: Getting Started Figure 3-1 6" Thimble Exhaust Connection to Outside (all dimension in inches) 16 Product Service 1-800-522-7658
Chapter 3: Getting Started Figure 3-2 Positive Pressure Glove Box Configuration (shown with a portion of the front panel removed) Product Service 1-800-522-7658 17
Chapter 3: Getting Started Installation of Gloves to the Glove Ports With thumbs up and right/left orientation, secure the gloves in place on the glove ports by stretching the beaded cuff into the groove nearest the window. Install the separate 8" diameter O-ring over the gloves and into the outer groove of the glove port surface. Stainless steel band clamps are provided for securing the separate O-ring into the glove port groove.
Chapter 3: Getting Started Setting the Exhaust Volume with the Speed Control Adjustment For Protector Filtered Glove Boxes, the speed control located on the front panel of the transfer chamber adjusts the exhaust air volume. The exhaust air volume should be adjusted to the lower settings for weigh operations. (Consult your Safety Officer for airflow recommendations for your application). Working at the lowest exhaust volume appropriate for the application will give the quietest operation.
Chapter 3: Getting Started Summary of Performance Testing Results Labconco’s test results show that the Protector Filtered Glove Box meets all the performance criteria when operated at 50% airflow volumes (50% inflow corresponds to 42 CFM or less for weighing with an analytical balance or handling powders; and 35-42 CFM or above for safe air clean up).
Chapter 3: Getting Started • Static pressure measured inside the glove box varied from negative .12 inches of water column at 15-CFM to negative 1.28 inches of water at 84CFM. The total system static pressure as measured between the exhaust filter and the blower varied from negative 0.31 inches of water column at 15-CFM to negative 2.48 inches of water at 84-CFM. • Displacement (vibration level) measured on the work surface is negligible at minimum through maximum airflow volume settings.
Chapter 4: Performance Features and Safety Precautions Performance Features The Protector Filtered Glove Box is designed to provide superior particulate containment. The filtered glove boxes have been tested to effectively contain toxic and noxious materials when properly installed and operated. Labconco engineered the filtered glove boxes to minimize the effects of turbulence. The concentrations of particulate materials in the main chamber are determined by the frequency of main chamber air volume changes.
Chapter 4: Performance Features and Safety Precautions 3. Particulate containment <20 nanograms per cubic meter as confirmed by SafeBridge Consultants, Incorporated. 4. Fast “clean up time.” 0.05 ppm average tracer gas levels or less detected during perimeter scan testing (surpasses ASHRAE 110 standards) after 5 minute dilution. 5.
Chapter 4: Performance Features and Safety Precautions Figure 4-1 Performance Features 24 Product Service 1-800-522-7658
Chapter 4: Performance Features and Safety Precautions Safety Precautions 1. It is the responsibility of the user to determine the suitability of this product for the intended applications. Consult your Safety Officer. 2. Prior to using the glove box, check to make sure that the exhaust blower is operating and that air is entering the glove box by observing the static pressure gauge. 3. Use good housekeeping in the glove box at all times. Clean up spills immediately. Periodically clean glove box interior.
Chapter 4: Performance Features and Safety Precautions 13. The surface of the HEPA or ULPA filter is fragile and should not be touched. Care must be taken to avoid puncturing the filter during installation or normal operation. If you suspect that a filter has been damaged DO NOT use the glove box; contact a local certification agency or Safety Officer. 14. The filters in the glove box will gradually accumulate airborne particulate matter from the room and from work performed in the glove box.
Chapter 5: Using Your Glove Box Now that the installation of your glove box is completed, you are ready to use your Protector Filtered Glove Box. Read this chapter to learn about: • Starting the Filtered Glove Box • Control Panel Touch Pad • All Program Screens • Routine Daily Work Procedures • Appropriate HEPA Filter Applications, Suitability and Guidelines • Definition of Terms • Appropriate Chemicals for Carbon Filters • Acid Use Starting the Filtered Glove Box 1.
Chapter 5: Using Your Glove Box Control Panel Touchpad The touchpad of the Protector Filtered Glove Box is shown below. Take a moment to get familiar with the buttons, their location and function. Also familiarize yourself with the display located on the front. The display will report system functions, such as airflow status, pressure status, timer displays, low airflow alarm messages, and low pressure alarm messages. Figure 5-1 Menu Button – This button toggles the display between menu modes.
Chapter 5: Using Your Glove Box All Program Screens 4 KEYS MENU, ▲, ▼, ENTER Press MENU key MENU OPTIONS ▲▼ to Choose, ENTER to Select, MENU to Exit 1. Setup 2. Timer SETUP 1. 2. 3. 4. 5. Units of Measure Security Lock Calibration Restore Defaults Diagnostic Enter Enter *Security Lock Code 234. Security Lock can prevent unauthorized personnel from changing settings. When Security Lock is ON, the unit will only allow the user to enter in a security lock.
Chapter 5: Using Your Glove Box Main Setup Screens SETUP (cont.) 1. 2. 3. 4. 5. Units of Measure Security Lock Calibration Restore Defaults Diagnostic Enter CALIBRATION LOCK ▲▼ to Choose, ENTER to Select, MENU to Exit Certifier’s Use Only! 234 code to access calibration mode. 0 Enter Enter RESTORE DEFAULTS All User Data will be reset except calibration. UP to Select MENU to Escape DIAGNOSTIC TEST ▲▼ to Choose, ENTER to Select, MENU to Exit f 1. Keypad 2. Airflow Sensor 3.
Chapter 5: Using Your Glove Box Calibration Program Screens AIRFLOW SENSOR AUTO-ZERO 1. Disable 2. Enable AIRFLOW SENSOR ZERO Enable Please Wait: 150 AIRFLOW SENSOR ZERO CALIBRATION LOCK ?? to Choose, ENTER to Select, MENU to Exit 0 Please Wait: 150 AIRFLOW SENSOR 1. Zero Adjust 2.
Chapter 5: Using Your Glove Box Diagnostic Program Screens KEY PAD TEST All Keys Are Off. DIAGNOSTIC TEST ▲▼ to Choose, ENTER to Select, MENU to Exit f 1. Keypad 2. Airflow Sensor 3. Pressure Sensor AIRLFOW X1: X5: X5 CAL: Airflow: SENSOR 261/XXX 212/XXX 134/212 70/70 CFM Airflow Sensor Diagnostic Notes: X5 CAL example represents a pressure of 134 with the blower off and 212 with the blower speed to produce 70 CFM for this calibration example. XXX, 134, and 212 are calibrated values for this example.
Chapter 5: Using Your Glove Box Routine Daily Work Procedures Planning • Thoroughly understand procedures and equipment required before beginning work. Start-up • Consult your Safety Officer for personal protective equipment recommendations. • Turn on exhaust blower and light. • Allow the enclosure to operate for 2-5 minutes at 50-100% blower speed. Loading Materials and Equipment • Load only the materials required for the procedure. Do not overload the glove box.
Chapter 5: Using Your Glove Box Appropriate HEPA or ULPA Filter Applications, Suitability and Guidelines • Microbiological materials and hazardous solids containment protecting only the operator and the surrounding environment. • Weighing of powders. • Containment of hazardous particulates using a HEPA or ULPA filter. • Powder or particulate procedures traditionally performed on an open bench.
Chapter 5: Using Your Glove Box point until the filter is replaced. (Note that the capacity of activated carbon is not a constant, but varies with the inlet concentration). Labconco Technical Specialists can determine with the computerized carbon-modeling program the estimated time saturation for a particular chemical. When using a HEPA or ULPA filter in all filtered glove boxes or in combination with a carbon filter, the speed control will need to be increased to allow for filter loading.
Chapter 5: Using Your Glove Box Prohibited Acid Use The Protector Stainless Steel Filtered Glove Box and internal metal parts must not be exposed to mineral acid use. No exceptions are permitted, as the glove box life span will be limited with mineral acid use. The door latch metal components and other metal parts inside the Protector Fiberglass Filtered Glove Box are susceptible to mineral acid use. However, the fiberglass liner by itself has superior chemical resistance over the stainless steel liner.
Chapter 6: Maintaining Your Glove Box Review this chapter on maintenance for the following: 1. Routine maintenance. 2. Decontamination. 3. Determining when to replace the filters. 4. How to install new filters. 5. HEPA or ULPA filter leak test. 6. Initial certification. 7. Re-certification. 8. Fluorescent light replacement. 9. Motorized impeller replacement. 10. Speed control replacement. 11. Airflow/Pressure monitor circuit board replacement.
Chapter 6: Maintaining Your Glove Box Routine Maintenance Schedule Weekly • Wipe down the interior surfaces of the glove box with a disinfectant or cleaner, depending upon the application. • Using a damp cloth, clean the exterior surfaces of the glove box, particularly the front and top, to remove any accumulated dust. • Operate the exhaust system, noting the airflow through the glove box to effectively remove a source of visible smoke.
Chapter 6: Maintaining Your Glove Box Determining When to Replace Filters The HEPA or ULPA filters in the filtered glove boxes gradually accumulate airborne particulate matter and powders from the enclosure and room. The rate of accumulation will depend upon the cleanliness of the room air, the amount of time the enclosure is operating, and the nature of work being done in the enclosure. In typical installations and usage, the filters will last two to five years before requiring replacement.
Chapter 6: Maintaining Your Glove Box 9. Turn the glove box ON and proceed to the Filter Leak Test in Chapter 6. 10. Reinstall the top metal cover.
Chapter 6: Maintaining Your Glove Box HEPA or ULPA Filter Leak Test Purpose This test is performed to determine the integrity of the filter(s), the filter housing, and the filter mounting frames. The leak test is to be done by a qualified technician with calibrated equipment. Reference Leak Testing and Photometer scanning from the Institute of Environmental Services (IES-RPCC001.3) Equipment Required 1. An aerosol photometer ATI model 2D, 2E, 2G or equivalent. Air Techniques Hamilton Associates Inc.
Chapter 6: Maintaining Your Glove Box 7. Ensure that the glove box speed control is adjusted to the maximum setting and the blower is exhausting 55-100 CFM through the glove box. 8. Position the aerosol generator discharge near the internal opening of each filter. Check both filters. 9. Start the aerosol generator. Ensure that the generator is operating with 1 nozzle on at 10 PSIG. 10. Allow the generator to operate for a minimum of 15 seconds.
Chapter 6: Maintaining Your Glove Box test port. Connect this tube to the “downstream” sampling port of the photometer. Acceptance The downstream average penetration shall not exceed 0.005 percent as measured by the photometer. Initial Certification The Protector Filtered Glove Box has been leak tested at the factory with helium gas at positive 1" w.g. pressure; leaks cannot exceed 1 x 10-6 cc/sec.
Chapter 6: Maintaining Your Glove Box Fluorescent Bulb Spring Clip Fluorescent Bulbs Front panel screw location Fluorescent Bulb Light Socket Figure 6-2 Lights Replacement 44 Product Service 1-800-522-7658
Chapter 6: Maintaining Your Glove Box Motorized Impeller Replacement The motorized impeller must be replaced as a complete unit. See Appendix A for replacement parts diagram. Consult your Safety Officer for proper decontamination or sealing of tubing before replacing the blower. 1. Unplug the motorized impeller from the electrical outlet. Refer to Appendix A for replacement parts. 2. Remove the hose connecting the exhaust filter to the motorized impeller. 3.
Chapter 6: Maintaining Your Glove Box Speed Control Replacement 1. Disconnect the power and remove the front control panel where the speed control is located. 2. Remove the two fasteners holding the speed control. Refer to Appendix A for replacement parts. 3. Disconnect all wires leading to the speed control as shown in Figure 6-4. Connect wires on new speed control in the same position as the old speed control. 4.
Chapter 6: Maintaining Your Glove Box Typical Circuit Board Connector Main Chamber Static Pressure, S.P., Port Closest to Circuit Board (Smaller Sensor) Speed Control and Wires Typical Circuit Board Mounting Screw Blower Total Pressure, T.P., Port Closest to Circuit Board (Larger Sensor) Silicone Larger I.D. Tubing Blower Static Pressure, S.P.
Chapter 7: Accessorizing Your Glove Box There are many ways to accessorize and modify the glove box for your individual requirements. These include many different accessories listed in this chapter. 1. Black Epoxy Flat Work Surface (Part #4882807) A solid epoxy resin 60" x 30" x 1.25" work surface is available to support the glove box. 2. 30" Standard Base Cabinet (Part #9900200) Two optional base cabinets may be ordered to support the 60" x 30" work surface and glove box.
Chapter 7: Accessorizing Your Glove Box 7. Balance Vibration Isolator (Part #5234600) Isolates building vibration and aids with balance weighing. Includes a 20" x 13" x 2 1/4" marble slab with isolator pads and type 304 stainless steel top cover to protect the porous marble. 8.
Chapter 7: Accessorizing Your Glove Box Part # 3970000 3970020 3970001 3970021 3970002 3970022 3970003 3970023 3970004 3970024 3707900 3923400 3923401 3923402 3776002 Descriptions 115V FilterMate (HEPA only included) 230V FilterMate (HEPA only included) 115V FilterMate (Carbon Filter sold separately) 230V FilterMate (Carbon Filter sold separately) 115V FilterMate w/thimble (HEPA included) 230V FilterMate w/thimble (HEPA included) 115V FilterMate Combination HEPA/Carbon (order Carbon Filter separately) 230
Chapter 7: Accessorizing Your Glove Box 19. Remote Blowers Has a 1/4 hp direct drive motor and corrosion-resistant epoxy-coated steel housing and wheel with blower inlet of 6.00" ID. Outlet dimensions are 4.25" x 7.38" OD. S.P. CFM Part # 4863500 4863501 0.0" 595 CFM @ Static Pressure-Inches of H2O 0.125" 0.25" 0.50" 0.75" 560 515 420 300 0.87" 167 Description Remote Blower, 115 V, 60 Hz. 4.4 amps Remote Blower, 115/230 V, 50 Hz, 5.6/2.8 amps Figure 7-1 All dimensions in inches 20.
Chapter 7: Accessorizing Your Glove Box Part # 7995600 5244100 5240100 Descriptions Ammonia Trap Insert Flowmeter, Visual Gas & Vacuum 0.2 Micron Filter 23. Polycarbonate Viewing Window with Frame (Part #5066700) Polycarbonate window, for those users that prefer polycarbonate over the standard laminated safety glass (includes metal frame). 24. Interior Glove Port Cover (Part #5060400) Quickly seals glove box should sudden leak occur due to glove damage.
Chapter 7: Accessorizing Your Glove Box 31. HEPA and ULPA Filters Part # 5225105 5225106 Descriptions Replacement Standard HEPA Filter, 99.99% efficient on 0.3 micron particles Optional ULPA Filter, 99.999% efficient on 0.3 micron particles 32. Inlet-Outlet Connection Kit – No HEPA (Part #5253400) The 3.
Chapter 8: Troubleshooting Refer to the following table if the Protector Filtered Glove Box fails to operate properly. If the suggested corrective actions do not solve your problem, contact Labconco for additional assistance. PROBLEM CAUSE CORRECTIVE ACTION Blower won’t operate. Unit not plugged into outlet. Plug the glove box into appropriate electrical service. Reset circuit breaker. Blower and lights won’t operate. Lights do not work. No power to electrical receptacle.
Appendix A: Replacement Parts The components that are available for your glove box are listed. The parts shown are the most commonly requested. If other parts are required, please contact Product Service. Item Qty. Part Number 1A 1B 2A 2B 2C 2D 3A 3B 3C 3D 3E 3F 3G 3H 1 1 1 1 0.01 quart 0.
Appendix A: Replacement Parts Item Qty.
Appendix A: Replacement Parts Figure A-1 Replacement Parts Product Service 1-800-522-7658 57
Appendix B: Dimensions See the following for all dimensions of the glove boxes. For conversion, 1" equals 25.4 mm. All dimensions are in inches.
Appendix C: Specifications This Appendix contains technical information about all the glove boxes including electrical specifications and environmental operating conditions. • All models: 12 Amps, 100-115V or 230V, 50/60 Hz • Single width units require one line cord and double width units require two line cords. Environmental Conditions • Indoor use only. • Maximum altitude: 6562 feet (2000 meters). • Ambient temperature range: 41° to 120°F (5° to 49°C).
Appendix D: Ionizer Fan Performance Criteria Static Electricity Test The tests were performed by monitoring the level of static electricity found on the work surface and interior surfaces within the glove box. Static electricity levels were measured with an AlphaLab Surface DC Voltmeter http://scientificmeter.com/surface_dc.htm. A DESCO Emit Mini Zero Volt Ionizer http://www.descoemit.com/ViewProduct.aspx?pid= 50661&h=1323 was installed in the glove box.
Appendix D: Ionizer Fan Performance Criteria Electrostatic with Glove Box Blower & Ionizer Fan OFF 100 CFM Blower & Ionizer Fan ON After 1 Hour 100 CFM Blower & Ionizer Fan ON After 2 Hours Metal Housing Inlet HEPA + 420 Test Point Locations and Voltage Levels Metal Metal Back Left Right Housing Transfer Interior FRP FRP Exhaust Chamber Surface Interior Interior HEPA Handle Surface Surface + 220 + 734 + 375 + 106 + 151 Center FRP Work Surface + 153 + 96 + 114 + 290 + 93 + 45 + 52 + 35 + 28 + 58
Appendix E: Conversions Pressure Conversions To From mmHg in.Hg in.H2O ft.H2O atm lb/in.2 Kg/cm2 kPa bar mmHg in.Hg in.H2O ft.H2O atm lb/in.2 Kg/cm2 kPa bar 1 25.40 1.868 22.42 760 51.71 735.6 7.500 750 .03937 1 .07355 .8826 29.92 2.036 28.96 .2953 29.53 .5353 13.60 1 12 406.8 27.69 393.7 4.016 401.6 .04461 1.133 .08333 1 33.90 2.307 32.81 .3347 33.47 .00132 .03342 .00246 .02950 1 .06805 .9678 .00987 .987 .01934 .4912 .03612 .4334 14.70 1 14.22 .1451 14.51 .00136 .03453 .00254 .03048 1.033 .
Appendix F: References Many excellent reference texts and booklets are currently available. The following is a brief listing: Pharmaceutical Isolators, A Guide to their application design and control. Pharmaceutical Press 2004, Editors: Midcalf, Phillips, Neiger, and Coles. Isolation Technology, A Practical Guide, 2004 CRC Press, 2nd Edition, www.crcpress.com International Standard ISO 10648-2 Containment Enclosures • Classification according to leak tightness and associated checking methods.
64 Product Service 1-800-522-7658
