User guide

Chapter 3: Getting Started
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8
Chemical Resistance of CentriVap
Components
Your CentriVap DNA Centrifugal Concentrator is designed to be chemical
resistant to most compounds that are commonly used in the concentration
processes that are performed in it. However, by necessity, the CentriVap is
comprised of a number of different materials, some of which may be attacked and
degraded by certain chemicals. The degree of degradation is obviously dependent
on the concentration and duration of exposure. Some major components of the
CentriVap that are susceptible to degradation are as follows:
Acids Bases Solvents
COMPONENT MATERIAL
Acetic Acid 20% Boric Acid Formic Acid Hydrobromic Acid 20% Hydrochloric Acid 20% Nitric Acid 20% Sulfuric Acid 10% Trifluoroacetic Acid (TFA) Ammonium Hydroxide Acetone Acetonitrile Chloroform Dimethyl Formamide Dimethyl Sulfoxide (DMSO) Ethanol Ethyl Acetate Hexanes Isoproponal Methanol Methylene Chloride Methyl t-Butyl Ether (MTBE) Toluene Water
Rotor Hub Polypropylene C D C
Lid Chamber Acrylic C D C D D D D C D D C D D
Chamber Epoxy coated
Aluminum
C D C D
Tubing PVC
D C D D D D D D C D D D D
Lid Gasket EPDM
D D C D
Rotor Anodized
Aluminum
DD
Rotor Shaft Stainless Steel D D D
Bearings High Carbon
Steel
D D D D D D D D D
C-Moderate Degradation-Questionable use
D-Severe Degradation-Infrequent use recommended-immediate thorough
cleaning required.
• Diaphragm vacuum pumps sold by Labconco have wetted parts either made
from PTFE or protected by PTFE coatings and are suitable for nearly all
procedures.