SDS

Product name: CARBOWAX™ POLYETHYLENE GLYCOL 3350
FLAKE (Inhibited)
Issue Date: 04/13/2015
Page 7 of 10
Evaluation of available data suggests that this material is not an STOT-SE toxicant.
Specific Target Organ Systemic Toxicity (Repeated Exposure)
Recent findings of kidney failure and death in burn patients, as well as some studies using animal burn
models, suggest that polyethylene glycol may have been a factor.
The use of topical applications containing this material may not be appropriate in severely burned
patients or individuals with impaired renal function.
Based on available data, repeated exposures are not anticipated to cause significant adverse effects.
Carcinogenicity
Polyethylene glycols did not cause cancer in long-term animal studies.
Teratogenicity
Did not cause birth defects or any other fetal effects in laboratory animals.
Reproductive toxicity
In animal studies, did not interfere with reproduction.
Mutagenicity
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.
Aspiration Hazard
Based on physical properties, not likely to be an aspiration hazard.
12. ECOLOGICAL INFORMATION
Ecotoxicological information on this product or its components appear in this section when such data
is available.
Toxicity
Acute toxicity to fish
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).
LC50, Pimephales promelas (fathead minnow), 96 Hour, 58,900 mg/l
Acute toxicity to aquatic invertebrates
EC50, Daphnia magna (Water flea), 48 Hour, 22,100 mg/l
Toxicity to bacteria
EC50, Bacteria, 16 Hour, > 10,000 mg/l
Persistence and degradability
Biodegradability: Material is readily biodegradable. Passes OECD test(s) for ready
biodegradability.
10-day Window: Pass
Biodegradation: 90 %
Exposure time: 28 d
Method: OECD Test Guideline 301B or Equivalent