Users Manual Part 1

Clinical User’s Guide IBA | xi |
Volume 1 - Treatment Session
Side Effects
Ionizing radiation can be harmful for living organisms. In the case of Radiation Oncology, ionizing radiation is used to treat patients with
localized tumors or other conditions susceptible to treatment by radiation. The benefit/risk of the treatment is evaluated by the Radiation
Oncologist who determines the amount of radiation that healthy tissues can safely receive with acceptable side effects. The Radiation
Oncologist and the clinical team are to define the best treatment plan (technique and dose) that will allow achieving the best risk (i.e.,
limitation of the undesirable side effects due to irradiation) / benefit (i.e., eradication of the tumors) ratio.
The following table summarizes the proton radiation treatment side effects published in literature.
(For references, see List of Published Literature.)
Pediatric
Adult
Eye CNS and Spine Head and Neck Lung Gastrointestinal Breast Prostate
Dry eye
15
Neovascular
glaucoma/
rubeosis
28
Nausea
vomiting
33
Dermatitis
45
Dermatitis
50
Fatigue
55
Radiation
dermatitis
59
Urinary
frequency or
urgency
63
Otitis
15
Maculopathy
29
Dermatitis
33
Mucositis
45
Fatigue
50
Erythema
55
Telangiectasia
59
Dysuria
63
Cataract
15
Secondary
glaucoma
30
Hearing loss,
Hypoacusis
33
Nausea
45
Hyper-
pigmentation
50
Inflammation or
ulceration within
the GI tract
55
Fat necrosis
59
Urinary
incontinence
63
Retinopathy
15
Dry eye
symdrome
31
Anemia,
leukopenia,
cytopenia,
thrombocyto-
penia
33
Vomiting
45
Anorexia
50
GI bleeding
55
Comesis score
60
Obstructive
symptoms
63