SDS

SAFETY DATA SHEET
HTH Shock Treatment
REVISION DATE : 06/24/2015 Page 9 of 13
the skin. However when wet, it will produce burns to the skin.
Subchronic / Chronic
Toxicity:
There are no known or reported effects from repeated exposure except those
secondary to burns.
Reproductive and
Developmental Toxicity:
Calcium hypochlorite has been tested for teratogenicity in laboratory
animals. Results of this study have shown that calcium hypochlorite is not a
teratogen.
Mutagenicity:
Calcium hypochlorite has been tested in the Dominant lethal assay in male
mice, and it did not induce a dominant lethal response. Calcium hypochlorite
has been reported to produce mutagenic activity in two in vitro assays. It
has, however, been shown to lack the capability to produce mutations in
animals based on results from the micronucleus assay. In vitro assays
frequently are inappropriate to judge the mutagenic potential of bactericidal
chemicals due to a high degree of cellular toxicity. The concentration which
produces mutations in these in vitro assays is significantly greater than the
concentrations used for disinfection. Based on high cellular toxicity in in vitro
assays and the lack of mutagenicity in animals, the risk of genetic damage
to humans is judged not significant.
Carcinogenicity:
This product is not known or reported to be carcinogenic by any reference
source including IARC, OSHA, NTP or EPA. One hundred mice were
exposed dermally 3 times a week for 18 months to a solution of calcium
hypochlorite. Histopathological examination failed to show an increased
incidence of tumors. IARC (International Agency for Research on Cancer)
reviewed studies conducted with several hypochlorite salts. IARC has
classified hypochlorite salts as having inadequate evidence for
carcinogenicity to humans and animals. IARC therefore considers
hypochlorite salts to be not classifiable as to their carcinogenicity to humans
(Group 3 Substance).
SECTION 12. ECOLOGICAL INFORMATION
Overview:
Highly toxic to fish and other aquatic organisms.
Ecological Toxicity Values - Product:
Bluegill
-
(nominal, static). 96 h LC50 Approximately 0.12 mg/l Based on
extrapolation from studies using calcium hypochlorite.
Rainbow trout (Salmo gairdneri),
-
(nominal, static). 96 h LC50 Approximately 0.22 mg/l Based on
extrapolation from studies using calcium hypochlorite.
Daphnia magna,
-
(nominal, static). 48 h LC50Approximately 0.15 mg/l Based on
extrapolation from studies using calcium hypochlorite.
Bobwhite quail
-
LC50 > 7,000 ppm Based on extrapolation from studies
using calcium hypochlorite.
Mallard ducklings
-
LC50 > 7,000 ppm Based on extrapolation from studies
using calcium hypochlorite.
Bobwhite quail
-
LD50 Approximately 4,800 mg/kg Based on extrapolation
from studies using calcium hypochlorite.