SDS

SAFETY DATA SHEET
HTH OTO TEST KIT - OTO SOLUTION
REVISION DATE : 06/17/2015 Page 6 of 10
SECTION 11. TOXICOLOGICAL INFORMATION
Component Animal Toxicology
Oral LD50 value:
HYDROCHLORIC ACID
LD50 900 mg/kg Rabbit
Component Animal Toxicology
Dermal LD50 value:
HYDROCHLORIC ACID
No data
Component Animal Toxicology
Inhalation LC50 value:
HYDROCHLORIC ACID
Inhalation LC50 1 h 3124 ppm Rat
Product Animal Toxicity
Oral LD50 value:
LD50 Believed to be approximately 3,000 mg/kg Rabbit
Dermal LD50 value:
No data
Inhalation LC50
value:
No data
Skin Irritation:
This material is expected to be corrosive.
Eye Irritation:
This material is expected to be corrosive.
Skin Sensitization:
This material is not known or reported to be a skin or respiratory sensitizer.
Subchronic / Chronic
Toxicity:
Not known or reported to cause subchronic or chronic toxicity.
Reproductive and
Developmental Toxicity:
Not known or reported to cause reproductive or developmental toxicity.
Mutagenicity:
Not known or reported to be mutagenic.
HYDROCHLORIC ACID
This chemical has been shown to be non-mutagenic
based on a battery of assays.
Orthotolidine dihydrochloride
This product has been tested for mutagenicity. Tests
revealed both positive and negative results.
Carcinogenicity:
This product is not known or reported to be carcinogenic by any reference
source including IARC, OSHA, NTP or EPA. However, based on the
orthotolidine dihydrochloride content and structurally related compounds
which have been found to cause cancer in laboratory animals and are
classified as possible human carcinogens, this product should also be
considered to be a possible human carcinogen. Caution should be used
when handling this product and exposures should be minimized.
HYDROCHLORIC ACID
The International Agency for Research on Cancer
(IARC) has classified this product or a component of
this product as a Group 3 substance, Unclassifiable as
to Its Carcinogenicity to Humans.