SDS

SAFETY DATA SHEET
Freon™ 410A (R-410A) Refrigerant
Version
10.5
Revision Date:
10/10/2020
SDS Number:
1336443-00045
Date of last issue: 02/27/2020
Date of first issue: 02/27/2017
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reproduction/developmental toxicity screening test
Species: Rat
Application Route: inhalation (gas)
Method: OECD Test Guideline 414
Result: negative
Test Type: Combined repeated dose toxicity study with the
reproduction/developmental toxicity screening test
Species: Rabbit
Application Route: inhalation (gas)
Method: OECD Test Guideline 414
Result: negative
Reproductive toxicity - As-
sessment
:
Weight of evidence does not support classification for repro-
ductive toxicity
STOT-single exposure
Not classified based on available information.
Components:
Difluoromethane:
Routes of exposure
:
inhalation (gas)
Assessment
:
No significant health effects observed in animals at concentra-
tions of 20000 ppmV/4h or less
STOT-repeated exposure
Not classified based on available information.
Components:
Difluoromethane:
Routes of exposure
:
inhalation (gas)
Assessment
:
No significant health effects observed in animals at concentra-
tions of 250 ppmV/6h/d or less.
Repeated dose toxicity
Components:
Pentafluoroethane:
Species
:
Rat
NOAEL
:
>= 50000 ppm
Application Route
:
inhalation (gas)
Exposure time
:
13 Weeks
Method
:
OECD Test Guideline 413
Difluoromethane:
Species
:
Rat, male and female
NOAEL
:
49100 ppm
LOAEL
:
> 49100 ppm
Application Route
:
inhalation (gas)
Exposure time
:
13 Weeks