Datasheet

SDS No.: 225573 V005.0
Pattex Repair Extreme
Page 9 of 13
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Trimethoxyvinylsilane
2768-02-7
not sensitising
Guinea pig maximisation
test
guinea pig
OECD Guideline 406 (Skin Sensitisation)
N-(3-
(Trimethoxysilyl)propyl)e
thylenediamine
1760-24-3
sensitising
Mouse local lymphnode
assay (LLNA)
guinea pig
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Trimethoxyvinylsilane
2768-02-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Trimethoxyvinylsilane
2768-02-7
positive
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Trimethoxyvinylsilane
2768-02-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Carcinogenicity
No data available.
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
Trimethoxyvinylsilane
2768-02-7
NOAEL P 250 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
Trimethoxyvinylsilane
2768-02-7
NOAEL P 1.000 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
Trimethoxyvinylsilane
2768-02-7
NOAEL F1 1.000 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
STOT-single exposure:
No data available.