MSDS

MATERIAL SAFETY DATA SHEET
Page 2 of 8
01/13/2005
Great Stuff
anticipated from swallowing small amounts incidental to normal handling
operations.
INHALATION: At room temperature, PMDI vapors are minimal due to low vapor
pressure. However, certain operations may generate vapor or aerosol
concentrations sufficient to cause irritation or other adverse effects.
Excessive exposure may cause irritation to upper respiratory tract and
lungs, and pulmonary edema (fluid in the lungs). May cause respiratory
sensitization in susceptible individuals. MDI concentrations below the
exposure guidelines may cause allergic respiratory reactions in individuals
already sensitized. Symptoms may include coughing, difficult breathing and
a feeling of tightness in the chest. Effects may be delayed. Decreased
lung function has been associated with overexposure to isocyanates.
In confined or poorly ventilated areas, propane and isobutane vapors can
readily accumulate and can cause unconsciousness and death due to
displacement of oxygen (simple asphyxia). Excessive exposure may increase
sensitivity to epinephrine and increase myocardial irritability (irregular
heartbeats). Signs and symptoms of excessive exposure may be central nervous
system effects. At air concentrations < 1000 ppm, propane exerts very
little physiological action; at 100,000 ppm and above it may produce
dizziness or other central nervous system effects. Signs and symptoms of
central nervous system depression, in order of increasing exposure, are
headache, dizziness, drowsiness, and unconsciousness, even death.
SYSTEMIC (OTHER TARGET ORGAN) EFFECTS: Tissue injury in the upper
respiratory tract and lungs has been observed in laboratory animals after
repeated excessive exposures to MDI/polymeric MDI aerosols.
CANCER INFORMATION: Lung tumors have been observed in laboratory animals
exposed to aerosol droplets of MDI/Polymeric MDI (6 mg/m3) for their
lifetime. Tumors occurred concurrently with respiratory irritation and lung
injury. Current exposure guidelines are expected to protect against these
effects reported for MDI.
TERATOLOGY (BIRTH DEFECTS): In laboratory animals, MDI/polymeric MDI did not
cause birth defects; other fetal effects occurred only at high doses which
EYE: Irrigate with flowing water immediately and continuously for 15
minutes. Consult medical personnel.
SKIN: Remove material from skin immediately by washing with soap and plenty
of water, (warm water is preferable if readily available). Remove
contaminated clothing and shoes while washing. Seek medical attention if
irritation persists. An MDI skin decontamination study demonstrated that
cleaning very soon after exposure is important, and that a polyglycol-based
skin cleanser or corn oil may be more effective than soap and water.
INGESTION: If swallowed, seek medical attention. Do not induce vomiting
unless directed to do so by medical personnel.
INHALATION: Remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, oxygen should be administered by
qualified personnel. Call a physician or transport to a medical facility.
NOTE TO PHYSICIAN: No specific antidote. Supportive care. Treatment based
on judgment of the physician in response to reactions of the patient. May
cause respiratory sensitization or asthma-like symptoms. Bronchodilators,
expectorants, and antitussives may be of help. Respiratory symptoms,
including pulmonary edema, may be delayed. Persons receiving significant
4. FIRST-AID MEASURES