Technical Specifications

Product Name: GREAT STUFF(TM) Window and Door Insulating
Foam Sealant STR 12oz HC ES
Issue Date: 06/10/2008
Page 7 of 12
Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after
repeated excessive exposures to MDI/polymeric MDI aerosols. Contains component(s) which have
been reported to cause effects on the following organs in animals: Kidney. Liver. Bone marrow.
Contains a component which is reported to be a weak organophosphate-type cholinesterase inhibitor.
Excessive exposure may produce organophosphate type cholinesterase inhibition. Signs and
symptoms of excessive exposure may be headache, dizziness, incoordination, muscle twitching,
tremors, nausea, abdominal cramps, diarrhea, sweating, pinpoint pupils, blurred vision, salivation,
tearing, tightness in chest, excessive urination, convulsions.
Chronic Toxicity and Carcinogenicity
Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of
MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory
irritation and lung injury. Current exposure guidelines are expected to protect against these effects
reported for MDI.
Developmental Toxicity
In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only
at high doses which were toxic to the mother.
Genetic Toxicology
In vitro genetic toxicity studies were negative for component(s) tested. Genetic toxicity data on MDI
are inconclusive. MDI was weakly positive in some in vitro studies; other in vitro studies were negative.
Animal mutagenicity studies were predominantly negative.
12. Ecological Information
ENVIRONMENTAL FATE
Data for Component: Diphenylmethane Diisocyanate, isomers and homologues
Movement & Partitioning
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction
with water forming predominantly insoluble polyureas.
Persistence and Degradability
In the aquatic and terrestrial environment, material reacts with water forming predominantly
insoluble polyureas which appear to be stable. In the atmospheric environment, material is
expected to have a short tropospheric half-life, based on calculations and by analogy with
related diisocyanates.
Data for Component: Polymethylenepolyphenyl polyisocyanate, polypropyleneglycol copolymer
Movement & Partitioning
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction
with water forming predominantly insoluble polyureas.
Persistence and Degradability
In the aquatic and terrestrial environment, material reacts with water forming predominantly
insoluble polyureas which appear to be stable. In the atmospheric environment, material is
expected to have a short tropospheric half-life, based on calculations and by analogy with
related diisocyanates.
Data for Component: Isocyanic acid, polymethylenepolyphenylene ester, polymer with
.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxypoly
Movement & Partitioning
In the aquatic and terrestrial environment, movement is expected to be limited by its reaction
with water forming predominantly insoluble polyureas.
Persistence and Degradability
In the aquatic and terrestrial environment, material reacts with water forming predominantly
insoluble polyureas which appear to be stable. In the atmospheric environment, material is
expected to have a short tropospheric half-life, based on calculations and by analogy with
related diisocyanates.