MSDS
11/07/2012Revision:
01/14/2013Printed:
6Page:
Goof Off Super Glue Remover
MATERIAL SAFETY DATA SHEET
09/14/2012Supercedes Revision:
type, in individuals exposed to varying concentrations of acetone. In most studies the subjects report discomfort,
irritation of the eyes and respiratory passages, mood swings, and nausea following exposure to acetone vapor at
concentrations of 500 ppm or higher. The fact that the effects subside following termination of exposure indicates
that acetone may be the active compound, rather than a metabolite. Case reports of accidental poisoning also
indicate that the effects (e.g., lethargy and drowsiness) are short-lived.
DEVELOPMENTAL/REPRODUCTIVE: Inhalation exposure to pregnant rats and mice did not cause
statistically significant malformations in the offspring, but did result in lower fetal body weights in both species.
Changes in testicular weight were observed in male rats following oral exposure and a premature menstrual period
occurred in 3 of 4 women acutely exposed by inhalation. The significance of these endpoints of reproductive
toxicity in men and women is unknown at this time.
CARCINOGEN STATUS: Not classifiable as to human carcinogenicity. Lack of data concerning carcinogenicity
in humans or animals.
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N-Methyl-2-Pyrrolidone:
ACUTE TOXICITY:
LD50 mouse, oral, 5,270 mg/kg, slightly toxic
LC50 rat, inhalation, >5.1 mg/L, 4 hr
LD50 rabbit, dermal, 4,000-8,000 mg/kg, moderately toxic
SKIN CORROSION / IRRITATION:
SERIOUS EYE DAMAGE / IRRITATION: Irritant (BASF-TEST)
RESPIRATORY OR SKIN SENSITIZATION: Not observed.
ASPIRATION HAZARD: No data.
MUTAGENIC DATA: Not observed.
IMMUNOTOXICITY: No data.
NEUROTOXICITY: No data.
DEVELOPMENTAL/REPRODUCTIVE: Contains material that may adversely effect the developing fetus
based on animal data. In animal studies NMP was embryotoxic by the oral, dermal and intraperitoneal routes, but
only after repeated high doses that approached the LD50 or were maternally toxic.
CARCINOGEN STATUS: Not a carcinogen.
Chronic Toxicological Effects
No data available.
Carcinogenicity/Other Information
ACGIH A4 - Not Classifiable as a Human Carcinogen.
A4n.a. n.a.
Hazardous Components (Chemical Name)
Acetone {2-Propanone} 67-64-1
CAS #
n.a.
NTP IARC ACGIH OSHA
1.
n.a.n.a. n.a.N-Methyl-2-pyrrolidone {2-Pyrrolidinone,
1-Methyl-; 1-Methylazacyclopentan-2-one}
872-50-4 n.a. 2.
12. Ecological Information
General Ecological Information
Acetone:
Toxicity:
LC50 /Oncorhynchus mykiss/ (Rainbow trout, weight 1.0 g) 5,540 mg/L/96 hr at 12 deg C (95% confidence limit
4,740-6,330 mg/L), /static bioassay/
LC50; Species: Oncorhynchus mykiss (Rainbow trout, fingerling, length 9.4 cm, weight 10.8 g); Conditions:
freshwater, flow through, 10 deg C, pH 8.0; Concentration: 6100 mg/L for 24 hr
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