Product Manual
Pain Ease has passed microbial examinations of
non-sterile products and is safe to be used prior
to aseptic procedures. It will not introduce or add
microorganisms to a site that has already been
cleansed with an antiseptic.
• Pain Ease is lled in a controlled environment which
undergoes microbial monitoring during each
manufacturing run.
• Lots of Pain Ease are tested to USP <61> and USP <62>
by an outside, independent laboratory. These tests
determine the total aerobic microbial count (TAMC)
and total yeast and mold counts (TYMC) present.
They also demonstrate that a substance is free
from Staphylococcus aureus (staph) and
Pseudomonas aeruginosa.
• Pain Ease contains a blend of high purity 1,1,1,3,3
Pentauoropropane (HFC-245fa) and pharmaceutical
grade 1,1,1,2 Tetrauoroethane (HFC-134a) to
control impurities.
“The vapocoolant
(Pain Ease) 1,1,1,3,3
pentauoropropane and
1,1,1,2-tetrauoroethane
is sprayed on skin
prepared with
povidone-iodine;
there is no statistically
signicant increase in
bacterial colonization.”
Schleicher WF, Richards BG, Huettner F, Ozturk
C, Zuccaro P, Zins JE. Skin sterility after applica-
tion of a vapocoolant spray. Dermatol Surg.
2014 Oct;40(10):1103-7. doi: 10.1097/01.
DSS.0000452654.29636.56.
Pain Ease
is safe for
Aseptic
Procedures
A Practitioner’s Guide to Gebauer’s Pain Ease
®