Specification

Oral (rat) LD50: 3306 mg/kg
[1]
Eye (rabbit): 5 mg - SEVERE
Legend:
1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS. Unless otherwise specified data
extracted from RTECS - Register of Toxic Effect of chemical Substances
PROPYLENE GLYCOL MONOMETHYL
ETHER - MIXTURE OF ISOMERS
for propylene glycol ethers (PGEs):
Typical propylene glycol ethers include propylene glycol n-butyl ether (PnB); dipropylene glycol n-butyl ether (DPnB); dipropylene glycol methyl
ether acetate (DPMA); tripropylene glycol methyl ether (TPM).
Testing of a wide variety of propylene glycol ethers Testing of a wide variety of propylene glycol ethers has shown that propylene glycol-based
ethers are less toxic than some ethers of the ethylene series. The common toxicities associated with the lower molecular weight homologues of the
ethylene series, such as adverse effects on reproductive organs, the developing embryo and fetus, blood (haemolytic effects), or thymus, are not
seen with the commercial-grade propylene glycol ethers.
The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants may produce
conjunctivitis.
NOTE: Exposure of pregnant rats and rabbits to the substance did not give rise to teratogenic effects at concentrations up to 3000 ppm. Fetotoxic
effects were seen in rats but not in rabbits at this concentration; maternal toxicity was noted in both species.
TITANIUM DIOXIDE
The material may produce moderate eye irritation leading to inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis.
Exposure to titanium dioxide is via inhalation, swallowing or skin contact. When inhaled, it may deposit in lung tissue and lymph nodes causing
dysfunction of the lungs and immune system. Absorption by the stomach and intestines depends on the size of the particle.
WARNING: This substance has been classified by the IARC as Group 2B: Possibly Carcinogenic to Humans.
* IUCLID
DIETHYLENE GLYCOL MONOBUTYL
ETHER
The material may produce severe irritation to the eye causing pronounced inflammation. Repeated or prolonged exposure to irritants may produce
conjunctivitis.
This category includes diethylene glycol ethyl ether (DGEE), diethylene glycol propyl ether (DGPE) diethylene glycol butyl ether (DGBE) and
diethylene glycol hexyl ether (DGHE) and their acetates. Studies show that they can cause kidney and liver damage, skin and eye irritation as well
as blood changes but do not cause damage to the reproductive, genetic and developmental abnormalities, sensitisation or respiratory systems.
However, DGEE is reported to cause sperm insufficiency.
PROPYLENE GLYCOL MONOMETHYL
ETHER - MIXTURE OF ISOMERS &
BIS(DIPHENYLPHOSPHINO)METHANE
No significant acute toxicological data identified in literature search.
PROPYLENE GLYCOL MONOMETHYL
ETHER - MIXTURE OF ISOMERS &
TITANIUM DIOXIDE
The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of
vesicles, scaling and thickening of the skin.
SODIUM ALUMINOSILICATE &
BIS(DIPHENYLPHOSPHINO)METHANE
Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition
known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key
criteria for the diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent
asthma-like symptoms within minutes to hours of a documented exposure to the irritant.
Acute Toxicity Carcinogenicity
Skin Irritation/Corrosion Reproductivity
Serious Eye
Damage/Irritation
STOT - Single Exposure
Respiratory or Skin
sensitisation
STOT - Repeated Exposure
Mutagenicity Aspiration Hazard
Legend:
– Data available but does not fill the criteria for classification
– Data available to make classification
– Data Not Available to make classification
SECTION 12 ECOLOGICAL INFORMATION
Toxicity
Ingredient Endpoint Test Duration (hr) Species Value Source
propylene glycol monomethyl
ether - mixture of isomers
LC50 96 Fish 1005.858mg/L 3
propylene glycol monomethyl
ether - mixture of isomers
EC50 48 Crustacea >500mg/L 1
propylene glycol monomethyl
ether - mixture of isomers
EC50 96 Algae or other aquatic plants 7152.973mg/L 3
propylene glycol monomethyl
ether - mixture of isomers
EC50 384 Crustacea 227.843mg/L 3
propylene glycol monomethyl
ether - mixture of isomers
NOEC 96 Fish =4600mg/L 1
titanium dioxide LC50 96 Fish 9.214mg/L 3
titanium dioxide EC50 48 Crustacea >10mg/L 2
titanium dioxide EC50 72 Algae or other aquatic plants 5.83mg/L 4
titanium dioxide EC20 72 Algae or other aquatic plants 1.81mg/L 4
titanium dioxide NOEC 336 Fish 0.089mg/L 4
sodium aluminosilicate LC50 96 Fish >1000mg/L 1
sodium aluminosilicate EC50 48 Crustacea 10001800mg/L 1
Chemwatch: 9-328075
Version No: 3.9
Page 7 of 10
Recon Ultra Smoke Odor Sealer - White 3092
Issue Date: 03/14/2017
Print Date: 03/14/2017
Continued...