Datasheet

Product name: DOWSIL™ 3145 RTV Mil-A-46146 Adhesive/Sealant
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Revision Date: 04.09.2020
Version: 4.0
Page 15 of 23
Methyltrimethoxysilane
In animal studies, did not interfere with reproduction.
octamethylcyclotetrasiloxane
In laboratory animal studies, effects on reproduction have been seen only at doses that
produced significant toxicity to the parent animals. In animal studies, has been shown to
interfere with fertility.
Dodecamethyl cyclohexasiloxane
No relevant data found.
Decamethylcyclopentasiloxane
In animal studies, did not interfere with reproduction.
Mutagenicity
Based on product testing: In vitro genetic toxicity studies were negative.
Information for components:
Methyltrimethoxysilane
In vitro genetic toxicity studies were negative in some cases and positive in other cases.
Animal genetic toxicity studies were negative.
octamethylcyclotetrasiloxane
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.
Dodecamethyl cyclohexasiloxane
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.
Decamethylcyclopentasiloxane
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.
SECTION 12: ECOLOGICAL INFORMATION
Ecotoxicological information appears in this section when such data is available.
12.1 Toxicity
Methyltrimethoxysilane
Acute toxicity to fish
Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50/LL50/EL50
greater than 100 mg/L in most sensitive species).
LC50, Oncorhynchus mykiss (rainbow trout), 96 Hour, > 110 mg/l, OECD Test Guideline 203
or Equivalent
Acute toxicity to aquatic invertebrates
EC50, Daphnia magna (Water flea), flow-through test, 48 Hour, > 122 mg/l, OECD Test
Guideline 202
Acute toxicity to algae/aquatic plants