Reference Guide

Performance evaluation and analysis
18 Reference Architecture of Dell EMC Ready Solution for HPC Life Sciences | Document 309
Figure 8 Performance comparisons between Lustre/MD3 and Lustre/ME4
3.2 De novo assembly performance
For de novo assembly, 8168 and 8280M are compared with the same amount of system memory, 1.5 TB in
R940. The main reason Cascade Lake 8280M was chosen is for its higher core counts and because it
supports more memory, which is beneficial ad the data size for de novo assembly continues to grow larger
over the time.
Table 3 Test bed for De Novo Assembly
Dell PowerEdge R940
Intel 1
st
Gen Xeon Scalable Processors
Intel 2
nd
Gen Xeon Scalable Processors
CPU
4x 8168
4x 8280M
Base Frequency (GHz)
2.7
2.7
Number of Cores
24
28
TDP (W)
205
205
Memory
48x 32 GB DDR4-2666 MHz, 2 DPC
24x 64 GB DDR4-2933 MHz, 1 DPC
Storage
18x 1.2TB SAS 12 Gbps, 10K in RAID 0
System Bios
2.1.3
Kernel
3.10.0-957.el7.x86_64
OS
Red Hat Enterprise Linux Server release 7.6
Sequence Reads
ERR318658, 3.2 Billion Reads of Whole Human Genome