User`s manual
ii Table of Contents
Calorimetry Sciences Corp.
CSC 5300 N-ITC III iii
User’s Manual
Reinstalling Software...........................................................11
CHAPTER THREE: THEORY OF OPERATION ........... 13
Introduction to Isothermal Titration Calorimetry .............13
Applications............................................................................14
Batch/Incremental Titration .................................................14
Titration/Data Analysis ........................................................16
Calculation of Equilibrium Constants..................................16
Mathematical Modeling.........................................................17
Introduction to Equilibrium Models ....................................17
Relating Heat, Enthalpy, and Binding Constants.................17
Fitting of Calorimetric Data .................................................21
CHAPTER FOUR: HARDWARE DESCRIPTION.......... 23
Description of Parts and Functions......................................23
Measuring Unit ....................................................................23
Reaction Vessel ....................................................................24
Syringe/Stirrer......................................................................24
Burette Assembly .................................................................25
USB Connection ..................................................................28
Power Supply.......................................................................29
Cleaning Tool.......................................................................29