MSDS

COMPARE•N•SAVE
®
CONCENTRATE MATERIAL SAFETY DATA SHEET
GRASS & WEED KILLER 41% GLYPHOSATE
Page 4 of 6 April 29, 2010
10. STABILITY AND REACTIVITY
Chemical Stability: This material is stable under normal handling and storage conditions.
Conditions to Avoid: Excessive heat. Do not store near heat or flame.
Incompatible Materials: Strong oxidizing agents: bases and acids. This product reacts with galvanized
steel or unlined steel (except stainless steel) to produce hydrogen gas that may form a highly combustible
gas mixture which could flash or explode.
Hazardous Decomposition Products: Under fire conditions, may produce gases such as nitrogen
oxides, carbon oxides and phosphorous oxides.
Hazardous Reactions: Hazardous polymerization will not occur.
11. TOXICOLOGICAL INFORMATION
Toxicological Data:
Data from laboratory studies conducted on a similar, but not identical, formulation:
Oral: Rat LD
50
: >5,000 mg/kg; FIFRA Category IV
Dermal: Rat LD
50
: >5,000 mg/kg; FIFRA Category IV
Inhalation: Rat 4-hr LC
50
: >2.05 mg/L; FIFRA Category IV
Eye Irritation: Rabbits (6): Moderately irritating (including transient corneal opacity) to unrinsed eyes.
Mildly irritating to rinsed eyes. Unrinsed eyes cleared by day 7 and rinsed eyes cleared by 72 hours;
FIFRA Category III
Skin Irritation: Rabbits (3); Slightly irritating. Cleared in all animals within 72 hours; FIFRA Category IV
Skin Sensitization: Not a contact sensitizer in guinea pigs following repeated skin exposure.
Toxicity of Isopropylamine Salt of Glyphosate:
In repeat dosing studies (6 month), dogs fed a more concentrated form of this product exhibited slight
body weight changes. Following repeated skin exposure (3 weeks) to this product, skin irritation was the
primary effect in rabbits. No skin allergy was observed in guinea pigs following repeated skin exposure.
Additional toxicity information is available on glyphosate, the active herbicidal ingredient of this product.
Following repeated exposures (90 days) to glyphosate in their feed, decreased weight gains were noted
at the highest test level in mice, while no treatment-related effects occurred in rats. Following repeated
skin exposure (3 weeks) to glyphosate, slight skin irritation was the primary effect observed in rabbits. No
skin allergy was observed in guinea pigs following repeated skin exposure. There was no evidence of
effects on the nervous system, including delayed effects in chickens (repeat oral doses) or cholinesterase
inhibition in rats (single oral doses). Reduced body weight gain and effects on liver tissues were
observed with long-term (2 year) feeding of glyphosate to mice at high-dose levels. Reduced body weight
gain and eye changes were observed at the high-dose level in one long-term (2 year) feeding study with
rats, while no treatment related effects occurred in a second study. No adverse effects were observed in
feeding studies with dogs. Glyphosate did not produce tumors in any of these studies.
Based on the results from the chronic studies, EPA has classified glyphosate in category E (evidence of
non-carcinogenicity for humans). No birth defects were noted in rats and rabbits given glyphosate orally
during pregnancy, even at amounts which produced adverse effects on the mothers. Glyphosate was fed
continuously to rats at very high dose levels for 2 successive generations. Toxicity was reported in
offspring from the high dose, a level which also produced adverse effects on the mothers. In a 3
generation study conducted at lower dose levels, no effects were seen on the ability of male or female
rats to reproduce. Glyphosate has produced no genetic changes in a variety of standard tests using
animals and animal or bacterial cells.
Toxicity of Ethoxylated Tallowamine:
The surfactant component of this product is reported to cause irritation to the eyes and skin and may
contribute to the irritation potential reported for this herbicide. Ingestion may product gastrointestinal
irritation, nausea, vomiting and diarrhea.