User guide

Lactam bridges -You can form lactam bridges between residues with available amino and carboxylic acid leaving
groups, such as Lys-Asp and Lys-Glu. For more information, see "Lactam bridges " on page 75.
Merging sequences- You can merge multiple sequences into one sequence by bonding together their terminal res-
idues.
Hybrid biopolymers - You can create hybrid (also called 'chimeric') biopolymers containing peptide, nucleotide, and
linker residues, using the Biopolymer toolbar. For more information, see "Hybrid biopolymers" on page 69.
Pasting sequences - You can paste sequences in the FASTA format. You can also copy a text string describing a
biopolymer as a series of single or multi letter residues, with valid separators (space, tab, dash), and paste it as a
sequence. The text string can be generated within or outside of ChemBioDraw. See "Pasting sequences" on page
63.
Displaying expanded residues - Expanded residues can appear in either linear mode or zigzag mode.
Expanding and contracting labels - You can expand the entire sequence or any part of it. The sequence will be auto-
matically cleaned following expansion.
When you contract a sequence, the Clean Up Biopolymer command cleans, and re-arranges the sequence so
that the residues are aligned, and wrapped.
Numbering residues - You can display residue numbers above any residue. For more information, see "Numbering
residues" on page 69.
Hide/Show termini and bonds -You can hide bonds and termini without affecting the underlying chemistry.
Nickname Enhancements. In ChemBioDraw 13.0, many new residues like non-standard amino acids, nonstandard
nucleotides, linkers have been added to the nickname library. Defining nicknames is much easier and more flexible
now.For more information on nicknames, see "Defining nicknames" on page 115.
Struct>Name Enhancements. Struct>Name in ChemBioDraw 13.0 has been enhanced to support many homo-
polymers, copolymers and alternating polymers, and stoichiometry specified as bracket properties, including frac-
tional stoichiometry. For more information, see "Struct>Name " on page 120.
Electron Pushing. ChemBioDraw 13.0 introduces the Electron Pushing tool for illustrating electron transfer. For
more information, see "Electron and radical pushing" on page 109.
Gel Electrophoresis Tool. Gel electrophoresis separates molecules using an electric field applied to a gel matrix.
The gel electrophoresis tool in ChemBioDraw 13.0 works much like the TLC tool and lets you easily draw and mark
bands based on weight or distance. For more information, see "TLC" on page 145.
TLC Plate Enhancements. In ChemBioDraw 13.0, you can copy and drag spots between lanes. For more infor-
mation, see "TLC" on page 145.
ChemBioDraw 13.0
What’s new vii