User guide

definition example
Definitions are expanded into multiple complete molecules. If more than one site is present in the selection, the expan-
sion includes all permutations of substitutions. Expansions are generated in a new document.
To expand a generic structure:
1. Select one or more generic structures to expand.
Note: For alternative group/R-tables, you must select the alternative group label and the table must be selected. If
the label is selected but not the table, the label will not change in the expansion, and will appear as a label in all gen-
erated structures.
2. Go to Structure>Expand Generic Structure.
The structures are generated in a new document.
R-Logic queries
After you have your generic structure and a set of R-groups, you can use them to run queries against a structure data-
base. This is called an R-Logic query.
When you run an R-Logic query, you search for structures that all have the generic structure and a combination of your
R-groups. The combinations are based on a Boolean expression that you define. To prepare an R-Logic search, go to
Structure>R-Logic Query to open the R-Logic Query dialog box.
To define a query, select one or more R-groups in your structure and how many times it must occur. You can also indi-
cate that, if the first R-group condition is met, another R-group must also be found before the structure is returned as a
result. For example, consider this query structure:
ChemBioDraw 13.0
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