SDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000018075
BAYER ADVANCED 12 MONTH TREE & SHRUB
PROTECT & FEED CONCENTRATE
MSDS Version 1.0
Page 5 of 7
Acute Inhalation Toxicity
rat: LC50: > 5.3 mg/l
Exposure time: 4 h
Determined in the form of liquid aerosol.
rat: LC50: > 20 mg/l
Exposure time: 1 h
Determined in the form of liquid aerosol.
Extrapolated from the 4 hr LC50.
Skin Irritation
rabbit: No skin irritation.
Eye Irritation
rabbit: Minimally irritating.
Sensitization
guinea pig: Non-sensitizing.
Chronic Toxicity
Imidacloprid caused thyroid and/or liver effects in chronic dietary studies in rats
and dogs.
Assessment Carcinogenicity
Imidacloprid was not carcinogenic in studies in rats and mice.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive &
Developmental Toxicity
REPRODUCTION: Imidacloprid was not a reproductive toxicant in a multi-
generation study in rats.
DEVELOPMENTAL TOXICITY: Imidacloprid is not considered a primary
developmental toxicant in rats and rabbits. Developmental effects were
observed at doses that caused maternal toxicity.
Neurotoxicity
Imidacloprid showed slight behavioral and activity changes only at the highest
dose tested in neurotoxicity studies in rats. There were no correlating
morphological changes observed in the neural tissues.
Mutagenicity
Imidacloprid was not mutagenic or genotoxic based on the overall weight of
evidence in a battery of in vitro and in vivo tests.
SECTION 12. ECOLOGICAL INFORMATION