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Bayer Environmental Science
SAFETY DATA SHEET
BAYER ADVANCED 12 MONTH TREE & SHRUB PROTECT
& FEED CONCENTRATE II
8/12
Version 2.0 / USA Revision Date: 04/14/2014
102000017711
Print Date: 04/14/2014
Assessment toxicity to reproduction
Imidacloprid caused reproduction toxicity in a two-generation study in rats only at dose levels also toxic
to the parent animals. The reproduction toxicity seen with Imidacloprid is related to parental toxicity.
Clothianidin caused reproduction toxicity in a two-generation study in rats only at dose levels also toxic
to the parent animals. The reproduction toxicity seen with Clothianidin is related to parental toxicity.
Assessment developmental toxicity
Imidacloprid caused developmental toxicity only at dose levels toxic to the dams. The developmental
effects seen with Imidacloprid are related to maternal toxicity.
Clothianidin did not cause developmental toxicity in rats.
Clothianidin caused developmental toxicity in rabbits only at dose levels toxic to the dams. The
developmental effects seen with Clothianidin are related to maternal toxicity.
Further information
Acute toxicity studies have been bridged from a similar formulation(s).
The non-acute information pertains to the active ingredient(s).
SECTION 12: ECOLOGICAL INFORMATION
Toxicity to fish
LC50 (Rainbow trout (Oncorhynchus mykiss)) 211 mg/l
Exposure time: 96 h
The value mentioned relates to the active ingredient imidacloprid.
LC50 (Rainbow trout (Oncorhynchus mykiss)) > 104.2 mg/l
Exposure time: 96 h
The value mentioned relates to the active ingredient clothianidin.
Toxicity to aquatic
invertebrates
EC50 (Water flea (Daphnia magna)) 85 mg/l
Exposure time: 48 h
The value mentioned relates to the active ingredient imidacloprid.
LC50 (Chironomus riparius (non-biting midge)) > 0.0552 mg/l
Exposure time: 24 h
The value mentioned relates to the active ingredient imidacloprid.
EC50 (Water flea (Daphnia magna)) > 40 mg/l
Exposure time: 48 h
The value mentioned relates to the active ingredient clothianidin.
EC15 (Chironomus riparius (non-biting midge)) 0.00072 mg/l
Exposure time: 28 d
The value mentioned relates to the active ingredient clothianidin.
EC50 (Chironomus riparius (non-biting midge)) 0.00106 mg/l
Exposure time: 28 d
The value mentioned relates to the active ingredient clothianidin.