SDS

Bayer Environmental Science
SAFETY DATA SHEET
BAYER ADVANCED ALL-IN-ONE ROSE & FLOWER CARE
READY-TO-USE GRANULES
7/11
Version 2.0 / USA Revision Date: 06/12/2014
102000021105
Print Date: 06/12/2014
Imidacloprid did not cause specific target organ toxicity in experimental animal studies.
Clothianidin did not cause specific target organ toxicity in experimental animal studies.
Assessment Mutagenicity
Tebuconazole was not mutagenic or genotoxic in a battery of in vitro and in vivo tests.
Imidacloprid was not mutagenic or genotoxic based on the overall weight of evidence in a battery of in
vitro and in vivo tests.
Clothianidin was not mutagenic or genotoxic based on the overall weight of evidence in a battery of in
vitro and in vivo tests.
Assessment Carcinogenicity
Tebuconazole caused at high dose levels an increased incidence of tumours in mice in the following
organ(s): liver. The mechanism of tumour formation is not considered to be relevant to man.
Imidacloprid was not carcinogenic in lifetime feeding studies in rats and mice.
Clothianidin was not carcinogenic in lifetime feeding studies in rats and mice.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Assessment toxicity to reproduction
Tebuconazole caused reproduction toxicity in a two-generation study in rats only at dose levels also
toxic to the parent animals. The reproduction toxicity seen with Tebuconazole is related to parental
toxicity.
Imidacloprid caused reproduction toxicity in a two-generation study in rats only at dose levels also toxic
to the parent animals. The reproduction toxicity seen with Imidacloprid is related to parental toxicity.
Clothianidin caused reproduction toxicity in a two-generation study in rats only at dose levels also toxic
to the parent animals. The reproduction toxicity seen with Clothianidin is related to parental toxicity.
Assessment developmental toxicity
Tebuconazole caused developmental toxicity only at dose levels toxic to the dams. Tebuconazole
caused an increased incidence of post implantation losses, an increased incidence of non-specific
malformations.
Imidacloprid caused developmental toxicity only at dose levels toxic to the dams. The developmental
effects seen with Imidacloprid are related to maternal toxicity.
Clothianidin did not cause developmental toxicity in rats.
Clothianidin caused developmental toxicity in rabbits only at dose levels toxic to the dams. The
developmental effects seen with Clothianidin are related to maternal toxicity.
Further information
Acute toxicity studies have not been performed on this product as formulated.
Acute toxicity studies have been bridged from a similar formulation(s).