Product Manual

Monitoring group
(n=822)
in contamination level
(90th percentile)
Control group
(n=295)
56
%
DECREASE
DECREASE
14
%
0
%
50
%
100
%
Routine monitoring is
recommended to validate
engineering controls
and minimize hazardous
drug exposure
8,12
Current USP <797>, new USP <800>
standards and other safe handling guidelines
recommend routine testing, as needed,
to check for hazardous residue on various
surfaces and verify containment.
13
In a 15-month study investigating wipe
sample monitoring at regular intervals
8
:
 61
%
of wipe samples (N=1,269) were positive
for contamination at baseline.
 In the control group, contamination was tested
at cycle one and cycle five.
 In the monitoring group, contamination was tested
at all five cycles.
Almost 7 out of 10 participating pharmacies
stated that they had changed or would change their
work procedures as a consequence of these findings.
8
Reduction in contamination over five cycles
8
During the study, approximately 75%
of the monitoring group introduced cleaning
protocol changes as a result of monitoring.
8