SDS

Bayer Environmental Science
SAFETY DATA SHEET
BAYER ADVANCED 3-IN-1 INSECT, DISEASE & MITE
CONTROL CONCENTRATE I
7/10
Version 1.0 / USA
Revision Date: 02/23/2015
102000030487
Print Date: 07/13/2016
Acute inhalation toxicity
LC50 (male/female combined rat) > 5.125 mg/l
Exposure time: 4 h
Determined in the form of a respirable aerosol.
(actual)
LC50 (male/female combined rat) > 20.5 mg/l
Exposure time: 1 h
Determined in the form of a respirable aerosol.
Extrapolated from the 4 hr LC50.
(actual)
Acute dermal toxicity
LD50 (male/female combined rat) > 4,000 mg/kg
Skin irritation
Slight irritation (rabbit)
Eye irritation
Slight irritation (rabbit)
Sensitisation
Non-sensitizing. (guinea pig)
Assessment repeated dose toxicity
Tau-fluvalinate did not cause specific target organ toxicity in experimental animal studies.
Tebuconazole did not cause specific target organ toxicity in experimental animal studies.
Assessment Mutagenicity
Tau-fluvalinate was not mutagenic or genotoxic in a battery of in vitro and in vivo tests.
Tebuconazole was not mutagenic or genotoxic in a battery of in vitro and in vivo tests.
Assessment Carcinogenicity
Tau-fluvalinate was not carcinogenic in lifetime feeding studies in rats and mice.
Tebuconazole caused at high dose levels an increased incidence of tumours in mice in the following
organ(s): liver. The mechanism of tumour formation is not considered to be relevant to man.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Assessment toxicity to reproduction
Tau-fluvalinate did not cause reproductive toxicity in a two-generation study in rats.
Tebuconazole caused reproduction toxicity in a two-generation study in rats only at dose levels also
toxic to the parent animals. The reproduction toxicity seen with Tebuconazole is related to parental
toxicity.
Assessment developmental toxicity