MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000017711
BAYER ADVANCED 12-MONTH TREE & SHRUB
PROTECT AND FEED CONCENTRATE II
MSDS Version 1.0
Page 5 of 8
Acute inhalation toxicity
rat: LC50: > 2.7 mg/l
Exposure time: 4 h
Determined in the form of liquid aerosol.
Highest attainable concentration.
No deaths
rat: LC50: > 10.8 mg/l
Exposure time: 1 h
Determined in the form of liquid aerosol.
Extrapolated from the 4 hr LC50.
Skin irritation
rabbit: No skin irritation
Eye irritation
rabbit: Mild eye irritation.
Sensitisation
guinea pig: Non-sensitizing.
Chronic toxicity
Imidacloprid caused thyroid and/or liver effects in chronic dietary studies in rats
and dogs.
Clothianidin caused effects in the liver, kidney and/or ovaries following chronic
exposure to high doses in mice, rats and dogs.
Assessment Carcinogenicity
Imidacloprid was not carcinogenic in studies in rats and mice.
Clothianidin was not carcinogenic in lifetime feeding studies in rats and mice.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive toxicity
REPRODUCTION:
Imidacloprid was not a reproductive toxicant in a multi-generation study in rats.
Clothianidin is not considered a reproductive toxicant at non-maternally toxic
dose levels.
DEVELOPMENTAL TOXICITY:
Imidacloprid is not considered a primary developmental toxicant in rats and
rabbits. Developmental effects were observed at doses that caused maternal
toxicity.
Clothianidin was not a primary developmental toxicant in rats and rabbits.