MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000021169
BAYER ADVANCED 12-MONTH TREE & SHRUB
PROTECT AND FEED READY-TO-USE GRANULES II
MSDS Version 1.0
Page 5 of 8
SECTION 11. TOXICOLOGICAL INFORMATION
Acute toxicity studies have not been conducted on this product as formulated. The acute toxicity data
provided has been bridged from a similar product, Merit 0.5% on 32-5-7 Granular Fertilizer. The non-acute
information pertains to the active ingredients.
Acute oral toxicity
male/female combined rat: LD50: > 5,136 mg/kg
Acute dermal toxicity
male/female combined rat: LD50: > 2,000 mg/kg
Acute inhalation toxicity
male/female combined rat: LC50: > 5.016 mg/l
Exposure time: 4 h
Determined in the form of dust.
(actual)
male/female combined rat: LC50: > 20 mg/l
Exposure time: 1 h
Determined in the form of dust.
Extrapolated from the 4 hr LC50.
(actual)
Skin irritation
rabbit: Mild skin irritation.
Eye irritation
rabbit: Mild eye irritation.
Sensitisation
guinea pig: Non-sensitizing.
Chronic toxicity
Imidacloprid caused thyroid and/or liver effects in chronic dietary studies in rats
and dogs.
Clothianidin caused effects in the liver, kidney and/or ovaries following chronic
exposure to high doses in mice, rats and dogs.
Assessment Carcinogenicity
Imidacloprid was not carcinogenic in studies in rats and mice.
Clothianidin was not carcinogenic in lifetime feeding studies in rats and mice.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive toxicity
REPRODUCTION: Imidacloprid was not a reproductive toxicant in a multi-