MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000015315
BAYER ADVANCED 3-IN-1 INSECT, DISEASE, & MITE
CONTROL CONCENTRATE
MSDS Version 1.0
Page 5 of 7
TAU-FLUVALINATE caused clinical signs of pyrethroid toxicity, decreased body
weights and/or liver effects in chronic toxicity studies in rats and dogs.
TEBUCONAZOLE caused liver, spleen, adrenal and/or eye effects at high doses
in chronic studies in rats and dogs.
Assessment Carcinogenicity
IMIDACLOPRID and TAU-FLUVALINATE were not considered carcinogenic in oncogenicity studies in rats
and mice.
TEBUCONAZOLE is classified by EPA as a Group C carcinogen (possible human carcinogen) based on
liver tumors in mice and no evidence of carcinogenicity in rats. As the liver tumors were seen only at a
dose exceeding a Maximum Tolerated Dose (MTD), no significant carcinogenic risk is posed for human
exposure.
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive &
Developmental Toxicity
REPRODUCTION: IMIDACLOPRID, TAU-FLUVALINATE and
TEBUCONAZOLE are not considered primary reproductive toxicants in rats.
Reproductive effects (e.g., decreased pup body weights) were observed at the
highest concentration but were considered secondary to maternal toxicity.
DEVELOPMENTAL TOXICITY: IMIDACLOPRID, TAU-FLUVALINATE and
TEBUCONAZOLE are not considered primary developmental toxicants in
laboratory animals. Developmental effects were observed only at doses that
caused maternal toxicity.
Neurotoxicity
IMIDACLOPRID and TEBUCONAZOLE caused only transient neurobehavioral
effects (e.g., decreased motor activity) in acute, subchronic and/or
developmental neurotoxicity studies in rats.
TAU-FLUVALINATE caused typical clinical signs associated with pyrethroid
neurotoxicity (e.g., transient hyperactivity) at high doses in rats.
Mutagenicity
IMIDACLOPRID, TAU-FLUVALINATE and TEBUCONAZOLE are not considered
genotoxic based on the overall weight of evidence in a battery of in vitro and in
vivo tests.
SECTION 12. ECOLOGICAL INFORMATION