MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000021105
BAYER ADVANCED ALL-IN-ONE ROSE & FLOWER CARE
READY-TO-USE GRANULES
MSDS Version 1.0
Page 5 of 8
SECTION 11. TOXICOLOGICAL INFORMATION
Acute toxicity studies have not been conducted on this product as formulated. The acute toxicity data
provided has been bridged from a similar product, Merit 0.5% on 32-5-7 Granular Fertilizer. The non-acute
information pertains to the active ingredients.
Acute oral toxicity
male/female combined rat: LD50: > 5,136 mg/kg
Acute dermal toxicity
male/female combined rat: LD50: > 2,000 mg/kg
Acute inhalation toxicity
male/female combined rat: LC50: > 5.016 mg/l
Exposure time: 4 h
Determined in the form of dust.
(actual)
male/female combined rat: LC50: > 20 mg/l
Exposure time: 1 h
Determined in the form of dust.
Extrapolated from the 4 hr LC50.
(actual)
Skin irritation
rabbit: Mild skin irritation.
Eye irritation
rabbit: Mild eye irritation.
Sensitisation
guinea pig: Non-sensitizing.
Chronic toxicity
Tebuconazole caused liver, spleen, adrenal and/or eye effects at high doses in
chronic studies in rats and dogs.
Imidacloprid caused thyroid and/or liver effects in chronic dietary studies in rats
and dogs.
Clothianidin caused effects in the liver, kidney and/or ovaries following chronic
exposure to high doses in mice, rats and dogs.
Assessment Carcinogenicity
Tebuconazole is classified by EPA as a Group C carcinogen (possible human carcinogen) based on liver
tumors in mice and no evidence of carcinogenicity in rats. As the liver tumors were seen only at a dose
exceeding a Maximum Tolerated Dose (MTD), no significant carcinogenic risk is posed for human
exposure.
Imidacloprid was not carcinogenic in studies in rats and mice.
Clothianidin was not carcinogenic in lifetime feeding studies in rats and mice.
ACGIH