MSDS

Bayer Environmental Science
Material Safety Data Sheet
MSDS Number: 102000016526
BAYER ADVANCED 24 HOUR GRUB KILLER PLUS I
READY-TO-SPREAD GRANULES
MSDS Version 1.0
Page 5 of 7
Skin Irritation
rabbit: Slight irritation.
Eye Irritation
rabbit: Moderate eye irritation.
Sensitization
guinea pig: Non-sensitizing.
Chronic Toxicity
Trichlorfon caused cholinesterase inhibition, anemia, hypercholesterolemia
and/or organ effects (liver, kidney, lung, stomach, intestinal) in chronic studies in
rats and monkeys.
Assessment Carcinogenicity
Trichlorfon was not carcinogenic in a lifetime feeding study in rats. In mice, trichlorfon caused an increased
incidence of epithelial mammary tumors in females at the excessive high dose. Based on these findings,
EPA has classified trichlorfon as "not likely to be carcinogenic to humans at low doses, but is likely to be
carcinogenic at high doses."
ACGIH
None.
NTP
None.
IARC
None.
OSHA
None.
Reproductive &
Developmental Toxicity
DEVELOPMENTAL TOXICITY: Trichlorfon is not considered a primary
developmental toxicant in rats and rabbits. Developmental effects were
observed at doses that caused maternal toxicity.
Neurotoxicity
Trichlorfon caused neurobehavioral effects ascribed to cholinergic toxicity in
acute and subchronic studies in rats. In addition, minimal micropathologic
findings were observed in the neural tissues of high-dosed rats following
subchronic exposure. In a one-generation developmental neurotoxicity study,
neurobehavioral effects were observed in the offspring without any correlating
micropathologic findings.
Mutagenicity
Trichlorfon has produced some positive results in a battery of in vitro and in vivo
tests.
SECTION 12. ECOLOGICAL INFORMATION
Environmental
Precautions
Do not allow to get into surface water, drains and ground water. Do not
contaminate surface or ground water by cleaning equipment or disposal of
wastes, including equipment wash water. Apply this product as specified on the
label.