User manual

80
A
B
Fig. 4.4.2.2.1. Add one extra Delay period after an LTD stimulation. A) LTD stimulation with no extra
Delay period. At the arrow, the ‘Repeat P0’ sweep button was clicked and a 20 pulse LTD stimulation (1
pulse/sweep) started after the last AvgLoop was exited. The 1
st
post-LTD pulse looked like 21st pulse of
LTD stimulation. B) LTD stimulation with one extra Delay period. At the arrow, the ‘Repeat P0’ sweep
button was clicked and a 20 pulse LTD stimulation started after the last AvgLoop was exited. The 1
st
post-LTD pulse was now clearly separated from the 20
th
pulse of the LTD stimulation.
If a single pulse is in ‘Pulse’ sweeps, repetitive pulse sweeps will produce LTD (Long-Term Depression)
stimulation.
In normal LTP experiments, a Pulse P0 Sweep generates S0 pulse stimulation only, and Fast Slow
Repetitive P0 Sweeps produces fast repetitive S0 pulse LTD stimulation. Similarly, a Pulse P1 Sweep
generates S1 pulse stimulation only, Fast Slow Repetitive P1 Sweeps produces fast repetitive S1 pulse
LTD stimulation.
4.4.2.3 Fast Repetitive Train Sweep (Theta) Stimulation
The check boxes in the ‘Fast Repeat Train Sweeps (Theta)’ panel in Fig. 4.4.2.1 (bottom of top panel)
determine whether these repeat train sweeps (T0 and T1) can be evoked by clicking single Run Buttons,