User guide

Cleaning and Maintenance
AB SCIEX TripleTOF
®
5600/5600+ Instruments
106 of 116
System User Guide
D5033331 A
This section provides instructions for performing routine cleaning without breaking vacuum and
full cleaning under atmospheric pressure, after venting the instrument.
Best Practices
• Always wear clean, powder-free gloves for the cleaning procedures.
• After cleaning the instrument components and before reassembling them, put on a
clean pair of gloves.
• Do not use cleaning supplies other than those specified in this procedure.
• If possible, prepare cleaning solutions just before beginning.
Note: Follow all applicable local regulations. For health and safety guidelines, refer to
Health and Safety Precautions for more information.
Required tools and materials
• Powder free gloves (nitrile recommended)
• Safety glasses
• Laboratory coat
• Fresh, high quality water (at least 18 Mohm de-ionized water [DI water] or ultra-pure HPLC-
grade water). Old water can contain contaminants which can further contaminate the mass
spectrometer.
• HPLC- or LCMS-grade methanol, isopropanol (2-propanol), or acetonitrile
• Cleaning solution. Use one of:
• 100% methanol
• 100% isopropanol
• 50:50 acetonitrile:water solution (freshly prepared)
• 50:50 acetonitrile:water with 0.1% acetic acid solution (freshly prepared)
Caution: Potential Instrument Damage: Do not use chlorinated solvents.
Note: For consumables ordering information and inquiries, call 877-740-2129 (U.S.
only), or visit www.absciex.com.
Table 8-2 Tools and Supplies Available from AB SCIEX
Description P/N
Small polyester swab (thermally bonded) 1017396
Small lint-free wipe (11 cm x 21 cm); available in Consumables kits WC018027
WARNING! Radiation Hazard, Biohazard, or Toxic Chemical Hazard:
Determine whether instrument decontamination is required prior to
cleaning. Instrument decontamination should be conducted prior to
cleaning if radioactive materials, biological agents, or toxic chemicals
have been used with an instrument.