MSDS

6110FR
Du Pont
Material Safety Data Sheet
Page 6
Printed on 10/13/2010
Other Hazards
Decomposition : Decomposition products are hazardous.
This material can be decomposed by high
temperatures (open flames, glowing metal
surfaces, etc.) forming hydrofluoric
acid, and possibly carbonyl halides.
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TOXICOLOGICAL INFORMATION
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Animal Data
The blend is untested.
HFC-125
Inhalation 4-hour ALC: >709,000 ppm in rats
Single exposure to high doses caused: Lethargy. Labored
breathing. Weak cardiac sensitization, a potentially fatal
disturbance of heart rhythm caused by a heightened
sensitivity to the action of epinephrine.
Lowest-Observed-Adverse-Effect-Level for cardiac
sensitization: 100,000 ppm.
Repeated exposure caused: No significant toxicological
effects. No-Observed-Adverse-Effect-Level(NOAEL): 50,000 ppm
ADDITIONAL TOXICOLOGICAL EFFECTS:
No animal data are available to define the following effects
of this material: carcinogenicity, reproductive toxicity.
In animal testing this material has not caused developmental
toxicity. Tests have shown that this material does not
cause genetic damage in bacterial or mammalian cell
cultures, or in animals. This material has not been tested
for its ability to cause permanent genetic damage in
reproductive cells of mammals (not tested for heritable
genetic damage).
HFC-32
Inhalation 4 hour-ALC: > 520,000 ppm in rats
Single exposure caused: Lethargy. Spasms. Loss of mobility
in the hind limbs. Other effects include weak cardiac
sensitization, a potentially fatal disturbance of heart
rhythm caused by a heightened sensitivity to the action of
epinephrine. 250,000 ppm.
Repeated exposure caused pathological changes of the lungs,
liver, spleen, kidneys. In more recent studies repeated
exposure caused: No significant toxicological effects.
No-Observed-Effect-Level (NOEL): 49,100 ppm.