CA Prop 65
  Proposition 65 in Plain Language  
  Office of Environmental Health Hazard Assessment 
   California Environmental Protection Agency 
What is Proposition 65? 
In 1986, California voters approved an initiative to address their growing concerns about 
exposure to toxic chemicals. That initiative became the Safe Drinking Water and Toxic 
Enforcement Act of 1986, better known by its original name of Proposition 65. 
Proposition 65 requires the State to publish a list of chemicals known to cause cancer or 
birth defects or other reproductive harm. This list, which must be updated at least once 
a year, has grown to include over 800 chemicals since it was first published in 1987. 
Proposition 65 requires businesses to notify Californians about significant amounts of 
chemicals in the products they purchase, in their homes or workplaces, or that are 
released into the environment. By providing this information, Proposition 65 enables 
Californians to make informed decisions about protecting themselves from exposure to 
these chemicals. Proposition 65 also prohibits California businesses from knowingly 
discharging significant amounts of listed chemicals into sources of drinking water. 
The Office of Environmental Health Hazard Assessment (OEHHA) administers the 
Proposition 65 program. OEHHA, which is part of the California Environmental 
Protection Agency (Cal/EPA), also evaluates all currently available scientific information 
on substances considered for placement on the Proposition 65 list.  
What types of chemicals are on the Proposition 65 list? 
The list contains a wide range of naturally occurring and synthetic chemicals that are 
known to cause cancer or birth defects or other reproductive harm. These chemicals 
include additives or ingredients in pesticides, common household products, food, drugs, 
dyes, or solvents. Listed chemicals may also be used in manufacturing and 
construction, or they may be byproducts of chemical processes, such as motor vehicle 
exhaust. 
How is a chemical added to the list? 
There are four principal ways for a chemical to be added to the Proposition 65 list. A 
chemical can be listed if either of two independent committees of scientists and health 
professionals finds that the chemical has been clearly shown to cause cancer or birth 
defects or other reproductive harm. These two committees—the Carcinogen 
Identification Committee (CIC) and the Developmental and Reproductive Toxicant 
(DART) Identification Committee—are part of OEHHA’s Science Advisory Board. The 





