User guide

Inlets 8
Advanced User Guide 235
Cold splitless introduction
For cold splitless introduction, use an initial inlet temperature
below the normal boiling point of the solvent. For most solvents,
starting the first inlet temperature ramp at 0.1 minutes
provides good transfer and reproducibility. A program rate of
500 °C/min or higher is appropriate for thermally stable
analytes. A final temperature of 350 °C, held for 5 minutes, has
quantitatively transferred up to C
44
alkane.
A main advantage of temperature programmability is that the
inlet can be heated gently to transfer delicate analytes. If the
oven temperature is initially low enough to refocus the analytes
on the column, the inlet heating rate can be made slower (e.g.,
120 °C/min). This reduces thermal degradation from the inlet
and can improve peak shape and quantitation.
Split vent flow
Purge flow
Saver flow
Inlet pressure
Inlet is
pressure
controlled
Post pressure
Inlet pressure
Inlet
temperature
Final temp 1
Initial temperature
Prep
Run
Start
Run
Purge
Time
Saver
Time
Stop
Run
Post
Time
Post
Time
Stop
Run
Purge
Time
Purge
Time
Prep
Run
Prep
Run
Start
Run
Start
Run
Column mode = Constant flow